Topical anaesthetics have been used in urology since 1884, when Pease described using “cocaine in a sensitive urethra with charming results”. Since 1949, 2% lidocaine has been increasingly used intraurethrally for cystoscopy and other procedures. This article is a pilot study (randomised, single-blinded) from Tel Aviv, comparing the efficacy of liquid paraffin with lidocaine in urodynamics. Twenty patients were included in each group. The instillation time was 10 minutes with penile clamp. Patients were asked to fill in a pain score chart (Score 0 -10 with 10 being the worst). The team found that liquid paraffin is superior to lidocaine. It appears that lubrication is more important than the presence of anaesthetic in the gel. Paraffin will require further studies and licensing if it is to be used widely in the future. 

Liquid paraffin is superior to 2% lidocaine gel in reducing urethral pain during urodynamic study in men: A pilot study.
Stav K, Taleb E, Sabler I, et al.
NEUROUROLOGY AND URODYNAMICS
2015;34:450-3.
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Arun K Sharma

West Herts NHS Trust (Watford General Hospital)

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