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Antibiotics and flexible cystoscopy
This study is from Memorial Sloan-Kettering Hospital in New York, USA. Thousands of flexible cystoscopies are performed every day worldwide. Do they need antibiotic cover? Flexible cystoscopy may cause urinary tract infection (UTI) in less than 10% of cases. Asymptomatic...
New therapy for overactive bladder
Overactive bladder (OAB) is a complex symptom that can adversely affect quality of life. So far pharmacotherapy has focused on anti-cholinergic drugs. Recently, beta-adrenoreceptors have been identified as having an effect on the detrusor muscle and urothelium. Beta-3 is the...
Is surgical antibiotic prophylaxis necessary for paediatric orchiopexy?
With the rise of resistant organisms to most commonly used antibiotics, there is a plea for judicious use of antibiotics, especially for clean surgical procedures. Potential adverse events associated with antibiotic use include allergic reaction (including anaphylaxis), clostridium difficile infection,...
Testicular prostheses satisfaction
This is a satisfaction survey in 40 patients who had underwent radical orchidectomy and had saline filled testicular prosthesis (TP) over a 3 year period in US, as the silicone implants are not in use since 1995 in US. No...
The survival impact of neoadjuvant hormonal therapy before radical prostatectomy
There is increasing evidence for the role of radical prostatectomy in select patients with T3-T4 prostate cancer (as part of multimodal therapy). This retrospective multicentre study explored the benefit of neoadjuvant hormonal therapy before radical prostatectomy specifically in patients with...
Long-term bladder drainage: blessing or disaster in disguise
Chronic bladder dysfunction occurs in many neurologic disorders e.g. multiple sclerosis, Parkinson’s disease, stroke, etc. Suprapubic catheters (SPC) are inserted every day and every urology department has a pool of ‘difficult’ patients who keep coming back. This paper compares SPCs...
Urethral sphincter function before and after radical prostatectomy
This paper from Holland will be useful for urologists involved in radical prostatectomy (RP) for cancer of the prostate. It presents a PubMed search between 1980 and 2012. Twenty-five out of 124 articles were further analysed, mainly English-language papers. Several...
Indication to pelvic lymph nodes dissection for prostate cancer
This paper explored the role of multiparametric MRI (mpMRI) in predicting the likelihood of lymph node invasion in patients with a risk of <5% according to the Briganti nomogram. Three hundred and ten patients who underwent a preoperative mpMRI and...
Reflux oesophagitis and risk of interstitial cystitis: is there a link?
This study aims to explore the potential link between reflux oesophagitis (RE) and interstitial cystitis / bladder pain syndrome (IC/BPS). IC/BPS is a chronic disease which is difficult to diagnose and treat. Two percent of the population may be affected....
Novel therapy for SUI
This is a joint study from Iran and University College London. Stress urinary incontinence (SUI) is a difficult condition to treat for patients and clinicians alike. Various surgical procedures have their benefits and pitfalls. Cell therapy is a new modality;...
Is renal pelvis reduction during dismembered pyeloplasty necessary?
The development of laparoscopic pyeloplasty has progressively led to a reduction in the amount of perioperative renal pelvic excision as a large excision leads to a longer anastomosis with associated increased risks (leak, operative time). This prospective study of 40...
