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Intermittent vs. continuous hormonal therapy for metastatic prostate cancer
Continuous androgen deprivation therapy (cADT) is the standard management for metastatic prostate cancer (mPCa). Intermittent androgen deprivation therapy (iADT) is sought to have better quality of life (QoL) and adverse events profile during off-treatment period. This multicentre European randomised study...
Testicular prostheses satisfaction
This is a satisfaction survey in 40 patients who had underwent radical orchidectomy and had saline filled testicular prosthesis (TP) over a 3 year period in US, as the silicone implants are not in use since 1995 in US. No...
The survival impact of neoadjuvant hormonal therapy before radical prostatectomy
There is increasing evidence for the role of radical prostatectomy in select patients with T3-T4 prostate cancer (as part of multimodal therapy). This retrospective multicentre study explored the benefit of neoadjuvant hormonal therapy before radical prostatectomy specifically in patients with...
Incidental findings on modern imaging
Incidentalomas can be defined in a variety of ways: 1) Imaging abnormality in a healthy, asymptomatic patient; 2) Imaging abnormality not related to a patient’s symptoms or the organs in question; 3) Findings discovered by chance which can potentially affect...
Is renal pelvis reduction during dismembered pyeloplasty necessary?
The development of laparoscopic pyeloplasty has progressively led to a reduction in the amount of perioperative renal pelvic excision as a large excision leads to a longer anastomosis with associated increased risks (leak, operative time). This prospective study of 40...
MRI scans and cardiac devices
There is an increasing use of MRI in many urological disorders e.g. prostate cancer and renal cancer. Many patients with cardiac pacemakers or implantable cardioverter defibrillators (ICD) are denied access to MRI scans due to safety concerns. MRI is given...
Serum cholesterol and risk of high-grade prostate cancer: results from the REDUCE study
This study examined a cohort of non-statin using patients who participated in the REDUCE study. The REDUCE study included men who had an elevated prostate specific antigen (PSA) and a negative baseline prostate biopsy who then underwent year two and...
Incidence and risk factors of suicide after a prostate cancer diagnosis
This is an observational study looking at 1,281,393 men diagnosed with prostate cancer and 842,294 matched prostate cancer-free men. There was an overall increased relative risk of suicide of 2.01 in men diagnosed with prostate cancer compared to those without,...
The natural history of prostate cancer on MRI
Multiparametric MRI features heavily on a number of active surveillance protocols. This study looked at 86 men on active surveillance who had an mpMRI prior to 2013 to assess how lesions changed over time. Two blinded radiologists examined all the...
Non-urothelial tumours of bladder – impact on oncological outcomes
Non-urothelial bladder tumours are not very common and they are generally considered to be high risk tumours when compared to standard urothelial tumours. In this study the researchers analysed the oncological outcomes of patients with such histology in comparison to...June Medical’s Angela Spång wins top award at Goldman Sachs 10KSB
After a rigorous application and interview process, Angela Spång, Founder & Owner of award-winning medical device company, June Medical, secured a place on the Goldman Sachs 10KSB transformative programme. She embarked on what is considered to be a condensed mini...
