Journal Reviews archive for November 2026
Prostate size in transwomen on gender-affirming hormone therapy
This study examined prostate size and characteristics in transgender females (TF) receiving hormone therapy (HT) and androgen deprivation (AD). Although gender-affirming surgery may include orchiectomy and vaginoplasty, most TF and gender-nonconforming individuals who were assigned male at birth retain their...
Prevalence of germline pathogenic variants in patients with metastatic prostate cancer
In this study, 5.9% of Dutch patients with metastatic prostate cancer (mPCa) carried a germline pathogenic variant (gPV) in a DNA damage-repair (DDR) gene. Consistent with international data, gPVs in CHEK2, ATM and BRCA2 were significantly more common in mPCa...
Practice makes perfect – but does the HoLEP learning curve affect sexual function?
This article poses an interesting question: whilst we know there is an association with HoLEP and ejaculatory dysfunction (BAUS quotes a 90% risk for retrograde ejaculation), is this risk dependent on surgeon experience and their learning curve with HoLEP? This...
Comparing retroperitoneoscopic and endourological approaches for upper ureteric and renal pelvic calculi
Urinary tract stones affect approximately 5–10% of people in developed countries. Advances in urological treatment have provided several surgical options, including ureteroscopic lithotripsy (URSL), retrograde intrarenal surgery (RIRS), percutaneous nephrolithotomy (PCNL), extracorporeal shock wave lithotripsy (ESWL), and minimally invasive laparoscopic...
