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Tissue-based biomarkers steering clinical decisions in patients with urothelial cancer

Biomarkers play an essential role in the diagnosis and treatment of urothelial cancer (UC), with PD-L1, FGFR, and MMR proteins being the most clinically established. These biomarkers, derived from histological specimens, guide therapeutic decisions for bladder cancer (BCa) and upper...

From Peyronie to Foley: the backstories behind the urology legends

Eponyms play a significant role in the field of urology, serving as a bridge between historical medical discoveries and modern clinical practice. For urology trainees, understanding these eponyms is more than just memorising names; it enriches our grasp of key...

Testing radical prostatectomy in men with prostate cancer and oligometastases to the bone: a randomised controlled feasibility study

Prostate cancer is the commonest cancer and the second most frequent cause of cancer death in Western men [1]. The recent STAMPEDE data suggests a median survival of just 42.1 months in the control arm of metastatic men [2]. Current...

Sperm selection techniques in assisted reproductive technologies: state of the ART?

Infertility is the inability to achieve pregnancy following one year of regular, unprotected intercourse (in the fertile phase of the menstrual cycle). Infertility is a common problem that affects between 7 and 15% of couples worldwide, with male factor infertility...

Innovative catheter receives “bacteria-phobic™” claim approval from notified body: positive evaluation affirms device resistance to bacterial colonisation

Camstent Ltd’s coated catheter, which has been developed to limit attachment of bacteria to its surfaces, a known source of Catheter Acquired Urinary Tract Infection (CAUTI), has been awarded approval...

Challenges in urology during and after the COVID-19 pandemic: a trainee perspective

The COVID-19 pandemic has affected urological practice in many ways and at all levels. Social media has been set alight with the hashtag #NoTrainingTodayNoSurgeonsTomorrow highlighting the undesired consequences of the reduction in training opportunities. The impact has been considered by...

Erectile dysfunction part II: treatment

Introduction The identification of specific risk factors associated with erectile dysfunction (ED) allows patients with mild or moderate ED to undergo a series of lifestyle changes, which may provide enough improvement in the erectile function to avoid pharmacotherapies. Cessation of...

An MA in medical education – is it for you?

I have recently completed a three-year MA in medical education at the University of Winchester, which has been an edifying experience. The following article may appeal to readers who are considering such a venture. I have been a consultant for...

Tackle Prostate Cancer: Make Sense of It Programme

Tackle Prostate Cancer is a small national charity with a big reach. We exist to ensure that people living with and affected by prostate cancer are not left to navigate diagnosis, treatment decisions and life after treatment on their own....

Relax and take note of this!

Children with neurogenic bladders are at risk of renal compromise through high detrusor pressures. Management aims to provide continence and preserve the upper tracts by increasing capacity and compliance though early clean intermittent catheterisation and anticholinergics. Intradetrusor botulinum toxin has...

Cadaveric Open Radical Cystectomy and Urinary Diversion Surgical Skills Course

This surgical skills course has been developed to enhance surgical skills in open radical cystectomy and urinary diversion techniques.

Post-Brexit deal welcomed but leaves future relationship with EU far from settled

This article was originally published EYE NEWS VOLUME 27 ISSUE 6 APRIL/MAY 2021 Rod McNeil breaks down the impact of the Brexit deal on healthcare in the UK, including medicines regulation, research funding, sharing of information and the ability to...