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PDE5I in LUTS – how do they work – no proof yet
Phosphodiesterase type 5 (PDE5) inhibitors used in erectile dysfunction (ED) have been shown to improve lower urinary tract symptoms (LUTS) as well. The mechanism is not well understood. One of the hypotheses for benign prostatic hyperplasia (BPH) – LUTS is...
Is routine renal tumour biopsy associated with lower rates of benign histology following nephrectomy for small renal masses?
There has been a considerable increase in the detection of small renal masses (SRM). Approximately 20% of these turn out to be benign lesions on final histopathological analysis. Therefore upfront surgery can be overtreatment in such a group of patients....
Prostate cancer mortality among elderly men after discontinuing organised screening
This study presents ground-breaking insights into discontinuing prostate cancer (PCa) screening in previously screened elderly men, aiming to mitigate the risk of overdiagnosis and overtreatment in the face of other-cause mortality. Examining men aged 70–74 who had undergone prostate specific...From trainee to trainer: how to succeed as a new supervisor
One day you’re operating, you’re an ST7 registrar in your last few weeks before CCT, your consultant is in the corner or coffee room supervising at whatever level they deem necessary. Just a few short weeks later, you’re the ‘Day...Urology National Selection: tips and tricks for a successful interview process
We invited Dominic Brown, the top-ranking candidate from the Urology National Training Selection Interview 2023, to share his wisdom on the interview process. Dominic is currently an ST3 working in North West London. Kelly Ong, Urology News Trainees Sub-Editor. 1....
Prostate cancer and an electronic nose
So far the transrectal ultrasound guided (TRUS) biopsy has been the ‘gold standard’ for diagnosing prostate cancer. However, it is invasive and can lead to complications, so there is a need for new non-invasive diagnostic tools to avoid unnecessary biopsy...
Upper tract urothelial carcinoma following cystectomy
Metachronous upper tract urothelial cancer (UTUC) is encountered in about 5% of patients after radical cystectomy (RC) with a median time to diagnosis of 24-36 months after RC, and most are asymptomatic and detected by surveillance protocols. In this multivariate...
Nocturia: the debate goes on
This study is from Ghent, Belgium. Nocturia is one of the most bothersome lower urinary tract symptoms affecting both men and women. Key factors to consider in evaluating are nocturnal polyuria (NP) and reduced bladder capacity. NP with low osmolality...
Morbidity and mortality after surgery for LUTS
The market for bladder outflow obstruction surgery is currently wide open with new technologies such as Urolift® emerging. One of the key selling points of new technologies is the comparative safety and efficacy compared to traditional techniques such as transurethral...
Laparoscopic transposition of renal lower pole crossing vessels
The vascular hitch procedure for pelvi-ureteric junction obstruction (PUJO) was initially described by Hellstroem in1951 and has become popular again since the introduction of laparoscopy. There is still much controversy as to its efficiency. The authors of this paper analyse...
HPV prevalence in invasive penile cancer and association with clinical outcome
Penile cancer risks can be increased by a number of causes such as smoking, phimosis, poor hygiene, multiple sexual partners and history of gential warts or other sexually transmitted diseases. It has been found that circumcised men have a lower...
