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New drug hope for prostate cancer patients
• Hormone therapy is used to slow the progression of advanced prostate cancer, but cancers often develop resistance and continue to grow.• Research reveals that patients with higher levels of heat shock proteins have worse outcomes.• Targeting these proteins with...
Rare and Complex Urology
Diseases that are rare or of low prevalence pose challenges to provision of high-quality care because of limited available knowledge and sparse good-quality evidence regarding uncommon presentations, mechanisms of disease, and optimal treatments. Approximately 80% of rare diseases are of...Intravesical GAG replacement therapies for bladder pain syndrome / interstitial cystitis – an update
The barrier function of the glycosaminoglycan (GAG) layer of the urothelium was identified by Parsons in 1975, and intravesical therapies to treat chronic inflammatory conditions of the bladder were developed soon after. However, the active role of the urothelium in...
Model to predict malignancy among Bosniak III cysts
This retrospective study over a 15-year period is to identify independent predictors of malignancy in Bosniak III (BIII) renal lesions and to build a prediction model based on identifiable clinical variables. These cysts, characterised by contrast-enhanced computed tomography (CECT), have...
Selective denervation of the bladder
The treatment of refractory overactive bladder is currently limited to neuromodulation (sacral nerve stimulation or percutaneous tibial nerve stimulation) or botulinum toxin injections. Although all these options are valuable, they have their own limitations and may not be suitable for...medac Pharma launch education platform, medac Academy
medac Pharma have launched a new digital education platform for UK healthcare professionals, medac Academy.NOVOGLAN – Conservative Phimosis Management
iMEDicare are pleased to introduce Novoglan, an evidence-based, non-surgical solution for adult phimosis, now available as a reimbursable outpatient treatment under the NHS OPCS-4 code N30.5 (Stretching of the Prepuce), which maps to HRG LB56A. This presents an exciting opportunity...Urodynamics in review: stress urinary incontinence in women produced by the Urodynamics Committee of the ICS
Urodynamic studies (UDS) are the best tools to objectively assess the lower urinary tract dysfunction (LUTD) of various aetiologies [1]. According to the general understanding and consensus of the medical community UDS should be performed only when they will change...
Prostate Cancer: Clinical Case Scenarios
This is a useful book to browse through, particularly for trainees. There are 195 pages of clinical information divided into 13 chapters. It’s a slim book which is easy to pick up and read. It uses case scenarios to discuss...
NICE - what we need to know?
The National institute for Health and Care Excellence (NICE) reached 17 years old in April 2016. As clinicians, we are reading and discussing NICE guidelines on a daily basis in multidisciplinary team meetings. NICE is always in the news, whether...
CROWN initiative – what is it about?
The editors of around 50 journals related to women’s health have joined forces to support the CROWN initiative (core outcomes in women’s health). The aim is to standardise the collection of outcomes for all trials in a specific dataset in...
