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Abiraterone acetate in men with castration-resistant prostate cancer

With emerging results from the Stampede and Latitude studies, abiraterone has taken the forefront in the management of metastatic prostate cancer while researchers try to identify the ideal timing for administration. It is a potent inhibitor of CYP17 which results...

Radium-223 treatment outcomes after multiple lines of mCRPC therapy in clinical practice: implication of pre-treatment spinal epidural disease

There are a number of treatments now available to patients with metastatic castrate-resistant prostate cancer (mCRPC). However, the optimal timing and order in which they are given is less clear. Radium-223 was FDA-approved for mCRPC patients with symptomatic bone metastases...

Predicting bone scan positivity in non-metastatic CRPC

There is evidence that suggests that early treatment with chemotherapy, immunotherapy or hormone therapy leads to a better response in patients with asymptomatic metastatic castrate resistant prostate cancer (CRPC). This study aimed to predict bone scan positivity in patients with...

The potential of statin use in castrate resistant prostate cancer treatment

One of the mechanisms by which prostate cancer achieves castrate resistance is through de novo intratumoral production of androgens. Reactivation of androgen receptors results in promotion of cell survival and proliferation pathways despite castrate serum testosterone levels. As androgen synthesis...

Digital Anatomy

Anatomy has been a cornerstone of medical and surgical education for hundreds of years. As an adjunct to traditional dissection-based teaching and textbooks, this month’s digital review guides you through some internet based anatomy resources. 3D models Anatomy for urology,...

UROsource

The European Association of Urology (EAU) has a new educational platform called UROsource, the learning library for urologists. The EAU library contains a searchable index of EAU conference proceedings, European Urology (EU) journals and EAU Guidelines. The searchable index is...

EAU Pocket Guidelines App

The European Association of Urology (EAU) has consistently led on the latest guidelines and advanced the care of urology since its inception. The EAU Pocket Guidelines app provides pocket guideline summaries of the full EAU Guidelines collection. The app is...

EAU Guidelines App

The European Association of Urology (EAU) continues to lead on the latest guidelines within urology. The all new EAU guidelines app brings together the pocket version of the EAU guidelines with a much improved user interface. Both the cancer and...

Cloud storage revisited

Cloud storage simply refers to digital files that are uploaded by users and stored remotely in the ‘cloud’ (usually these files are physically stored on servers owned by large companies e.g. Amazon, Microsoft, Dropbox and accessed via the web). In...