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Dogs and humans share a bladder cancer biomarker: a new discovery that opens doors for early detection and treatment

A new scientific study has identified a new molecular biomarker that could help doctors detect aggressive early-stage bladder cancer, such as high-grade non-muscle invasive bladder cancer (NMIBC), in both dogs and humans. This discovery advances our knowledge of how aggressive...

Interpretation of Urodynamic Studies

It does not matter if you are the kind of person who gets excited by books on urodynamics or someone who just wants to learn a new skill, you need to get your hands on this book as it blows...

MRI targeted transperineal prostate biopsy: a local anaesthetic approach

Transperineal template biopsy remains the gold standard investigation in diagnosis of prostate cancer. Data from the PROMIS study demonstrated the low sensitivity of transrectal ultrasound (TRUS) biopsy as a diagnostic tool, and highlighted the need for a better diagnostic pathway....

Is routine renal tumour biopsy associated with lower rates of benign histology following nephrectomy for small renal masses?

There has been a considerable increase in the detection of small renal masses (SRM). Approximately 20% of these turn out to be benign lesions on final histopathological analysis. Therefore upfront surgery can be overtreatment in such a group of patients....

History of prostate biopsy – part 1

Part 2 of this topic is available here. Prostate biopsy (PBx) to exclude cancer has been part of clinical practice since the beginning of the 20th Century. PBx techniques have evolved over time to optimally address some of the unique...

Purple urine bag syndrome

Purple urine bag syndrome (PUBS) is an uncommon phenomenon where the tubing and urinary catheter bag is noticed to undergo purple discolouration. This has been linked with urinary tract infections (UTI), chronic debilitated states and prolonged catheterisation. PUBS was noticed...

Visual-estimation (cognitive), image-fusion (software) and in-bore targeted prostate biopsy: is there an optimal approach?

The diagnostic superiority of multiparametric magnetic resonance imaging (mpMRI) prior to targeted and systematic prostate biopsy over systematic transrectal ultrasound-guided (TRUS) biopsy alone in the detection of clinically significant prostate cancer (csPCa) has been proven by multiple level 1 studies...

How do we tackle social injustice in urological cancer?

Socioeconomic status as an established determinant of health and associated injustices is well recognised. Confronting these injustices and creating a fairer healthcare system is an ongoing challenge for many governments. In Scotland, the devolved government has created the Scottish Index...

The risk of tumour recurrence in patients undergoing renal transplantation for end-stage renal disease

End stage renal disease (ESRD) patients in need of a kidney transplant who have a previous history of urological cancer should undergo a cancer-free waiting period before receiving a kidney transplant. Currently the recommended waiting time is based on the...

Nurse practitioner TRUS biopsy: training and preparation

As prostate cancer rates increase, many urology departments rely on multi-professional teams to diagnose and manage patients with prostate cancer. The aim of this article is to highlight the skills, training and preparation required for nurse practitioners to undertake trans-rectal...

Nonacus Clinical Services announce partnership with The London Clinic to deliver GALEAS™ Bladder test

Nonacus Clinical Services, the UK laboratory delivering genomic cancer testing services to the NHS and private healthcare providers, recently announced it is working with The London Clinic to help more patients benefit from its non-invasive GALEAS™ Bladder test for cancer....

Upper urinary tract urothelial cell carcinoma

Case 1 A 64-year-old man presents to the haematuria clinic with visible haematuria, on a background of a 40 pack-year smoking history and family history of bowel cancer in his sister at the age of 48. A CT was performed...