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Thiazide diuretic prophylaxis for kidney stones and the risk of diabetes mellitus

Thiazide diuretics have been used to reduce calcium nephrolithiasis recurrence as it is tolerated well, inexpensive and reduces calcium excretion in urine. It has been linked with increased risk of diabetes mellitus (DM) in the presence of hypertension (ALLHAT study),...

The role of transperineal template biopsies in the diagnosis of prostate cancer

The case In 2002, Mr A, a 64-year-old software engineer, was referred by his GP for further investigation of a raised prostate specific antigen (PSA) of 6.2. His prostate felt benign. He underwent transrectal ultrasound guided (TRUS) prostate biopsies. This...

Use of MRI in the evaluation of prostate cancer: part 1

Introduction Prostate cancer remains the most commonly diagnosed cancer in males and the second leading cause of cancer related deaths in UK men, after lung cancer [1]. The incidence of prostate cancer in the UK has shown a rapid increase...

Treating Urothelial Bladder Cancer

This is a short book comprising 129 pages of text which I read in one afternoon. It provides a useful update on one of the most common malignancies encountered by urologists worldwide, which experienced urologists and trainees alike would benefit...

Campbell-Walsh-Wein Handbook of Urology

Campbell’s Urology, as it is widely referred to, has the unassailable position of being the go-to reference text for urology. Incredibly, this is now available in a concise pocket version! It’s remarkable how such a vast quantity of information could...

Prostate cancer detection rate of MRI-TRUS fusion vs. systematic biopsy

With the advent of one-stop prostate cancer diagnostic clinics, the findings of this study are of interest to readers who may be considering introducing the technique of magnetic resonance imaging transrectal ultrasound (MRI-TRUS) fusion biopsies to their practice. A retrospective...

Screening tool for incontinence: Michigan index

The Michigan incontinence symptom index (MISI) is a validated measure. This study further evaluated its relevance. MISI is a 10-item measure; MISI domain 1-8 and bother domain 9-10. Two hundred and fourteen women were included in the study, with a...

Surgical management of DSD

The management of children with disorders of sex development (DSD) continues to be controversial. This editorial was written in response to a review article in the same edition on ‘Evidence regarding cosmetic and medically unnecessary surgery in infants’ by M...

Guideline of guidelines – testosterone therapy for testosterone deficiency

The authors conducted an internet search and analysed guidelines for testosterone therapy (TTh) produced by the American Urological Association (AUA), European Association of Urology (EAU), American Association of Clinical Endocrinologists (AACE), British Society of Sexual Medicine (BSSM), Endocrine Society (ES),...

Characteristics of APC and the usefulness of MP-MRI for diagnosis

The authors evaluated the pathological and oncological characteristics of anteriorly located prostate cancer (APC) in 728 RP specimens, and the accuracy of multiparametric magnetic resonance imaging (MP-MRI) for APC evaluation. Patients were characterised as APC (70% or more of tumour...

Urologists beware!

This article recounts the story of a Californian urologist who was shot dead two decades later by a patient who was diagnosed with stricture of the urethra. The patient underwent surgery for urethral stricture in 1992 by a team (ironically,...

Secondary bladder cancer following upper tract urothelial cancer

Upper tract urothelial carcinoma (UTUC) comprises <5% of all urothelial cancers. A certain proportion of patients with UTUC will develop secondary bladder urothelial cancer (BUC). This paper has retrospectively examined records obtained from several cancer USA population-based registries of more...