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Trials offering cytoreductive surgery for men with de novo synchronous metastatic prostate cancer
Life expectancy in men diagnosed with de novo synchronous metastatic hormone-sensitive prostate cancer (mHSPC) has risen to a median of 4.8 years with upfront systemic agents (such as docetaxel) in addition to standard androgen deprivation therapy (ADT) [1-3]. Within this...Sustainable healthcare: what steps can urologists take?
Human health is intrinsically linked to environmental health, making the ever-pressing climate crisis fundamentally a public health emergency. The healthcare sector is responsible for 8% of the UK’s greenhouse gas (GHG) emissions worldwide [1]. As the largest publicly funded healthcare...The microbial syndicate: dysbiosis and origins of recurrent UTIs
Traditional dogma held that urine was sterile. However, recent molecular studies have revealed an underground microbial community, known as the urinary microbiome or ‘urobiome’ [1]. Far from being harmful, this community of microorganisms helps modulate immune responses, regulate inflammation, and...Using change theories can help nurses implement better care in prostate cancer
Nurses can help support change in prostate cancer care by understanding change management and models and provide leadership in improving prostate cancer care. An important part of being able to lead change is to understand change theories such as the...New charity launches to highlight urethral strictures – men’s silent epidemic
A new charity, the Collaboration for Urological Research and Education (CURE), has today called for urgent action to address one of Britain’s biggest silent epidemics – urethral strictures. Launching Stricture Awareness Month (SAM) in March, CURE has called on healthcare...
Thiazide diuretic prophylaxis for kidney stones and the risk of diabetes mellitus
Thiazide diuretics have been used to reduce calcium nephrolithiasis recurrence as it is tolerated well, inexpensive and reduces calcium excretion in urine. It has been linked with increased risk of diabetes mellitus (DM) in the presence of hypertension (ALLHAT study),...Use of MRI in the evaluation of prostate cancer: part 1
Introduction Prostate cancer remains the most commonly diagnosed cancer in males and the second leading cause of cancer related deaths in UK men, after lung cancer [1]. The incidence of prostate cancer in the UK has shown a rapid increase...The role of transperineal template biopsies in the diagnosis of prostate cancer
The case In 2002, Mr A, a 64-year-old software engineer, was referred by his GP for further investigation of a raised prostate specific antigen (PSA) of 6.2. His prostate felt benign. He underwent transrectal ultrasound guided (TRUS) prostate biopsies. This...
Characteristics of APC and the usefulness of MP-MRI for diagnosis
The authors evaluated the pathological and oncological characteristics of anteriorly located prostate cancer (APC) in 728 RP specimens, and the accuracy of multiparametric magnetic resonance imaging (MP-MRI) for APC evaluation. Patients were characterised as APC (70% or more of tumour...
Treating Urothelial Bladder Cancer
This is a short book comprising 129 pages of text which I read in one afternoon. It provides a useful update on one of the most common malignancies encountered by urologists worldwide, which experienced urologists and trainees alike would benefit...
Campbell-Walsh-Wein Handbook of Urology
Campbell’s Urology, as it is widely referred to, has the unassailable position of being the go-to reference text for urology. Incredibly, this is now available in a concise pocket version! It’s remarkable how such a vast quantity of information could...
