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PET imaging of prostate-specific membrane antigen in prostate cancer
Molecular imaging utilising prostate-specific membrane antigen (PSMA) as a target has increasingly been mentioned at key conferences and meetings. PSMA is a membrane metalloenzyme that is overexpressed in prostate cancer, with the degree of expression appears to correlate with tumour...
How effective are intravesical therapies for bladder pain syndrome?
The objective of this study was to review the clinical efficacy of currently available products for the intravesical treatment of bladder pain syndrome (BPS) / interstitial cystitis (IC) and to assess their pharmaco-economic impact. Nineteen articles were reviewed, including five...
Research needs you
This was an eye-catching front cover headline for the BMJ. Is research as important as clinical duties? The answer has to be yes. Research takes place in every NHS hospital, albeit in a fragmented way. All of us have to...
Non-antibiotic options for recurrent UTI
Recurrent urinary tract infection (UTI) imposes a heavy burden on health services. By definition recurrent UTI is two infections in six months or three in one year. The annual incidence of single UTI is 30 per 1000 women. The Scottish...
BPH therapy: how to find one’s way through the maze?
This communication is from the Young Academic Urologists (YAU) group of the European Association of Urologists (EAU). A purpose-built questionnaire of current practice was sent to 2000 members, of which 637 responded (68% were aged 50 or younger). Alpha blockers...
New therapy for overactive bladder
Overactive bladder (OAB) is a complex symptom that can adversely affect quality of life. So far pharmacotherapy has focused on anti-cholinergic drugs. Recently, beta-adrenoreceptors have been identified as having an effect on the detrusor muscle and urothelium. Beta-3 is the...
Post prostatectomy outcomes of patients with high-risk prostate cancer treated with neoadjuvant androgen blockade
This is an interesting paper reporting on the use of neoadjuvant androgen blockage in patients with high-risk prostate cancer undergoing radical prostatectomy. Previous work in the literature has shown an improvement in the rate of organ-confined disease and decreased positive...Six times a day: Living with non-neurogenic bladder failure
A normal workday morning – my laptop is open and I have a glass of water within reach. What makes this different from a typical day in the life of most academics is that I will soon go to my...
