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To clamp or not to clamp – outcomes of the CLOCK trial for robotic partial nephrectomy
The benefits of partial over radical nephrectomy are well established. The CLOCK trial (CLamp vs. Off Clamp the Kidney during robotic partial nephrectomy) was designed as a multicentre, randomised controlled trial to generate evidence on the role of the off-clamp...
First and second-line treatments in metastatic renal cell carcinoma
Over the past two decades, the treatment landscape for metastatic renal cell carcinoma (mRCC) has evolved significantly, leading to a quadrupling of patient survival rates. Modern systemic treatments include combinations of anti-PD-1 antibodies with either anti-CTLA-4 antibodies or antiangiogenic tyrosine...New – unique 20ml pre-filled syringe hyaluronate GAG replenisher
Solatumfarma’s new sodium hyaluronate GAG replenisher offers to improve treatment for patients with chronic cystitis.Bladder cancer – an overshadowed ‘volcano’
Bladder cancer has often been overshadowed by the limelight of prostate cancer. However, of all the urological cancers, bladder cancer is the only one which has shown a slight decline in age-standardised five-year survival rates over the last couple of...Femeda Ltd Wins Prestigious Medilink Partnership with Academia Award
Partnership with Academia Award Winner: Femeda Ltd Femeda has committed to the first real world clinical trial for a consumer medical device globally to be run in Manchester. Femeda is extending the partnership with engagement of Phd students from the...Femeda Ltd Wins Prestigious Medilink Partnership with Academia Award
Femeda has committed to the first real world clinical trial for a consumer medical device globally to be run in Manchester. Femeda is extending the partnership with engagement of Phd students from...Conservative management of pelviureteric junction
Background Pelviureteric junction obstruction (PUJO) is defined as a functionally significant impairment of urine flow from the renal pelvis into the proximal ureter. For more than a century, surgery was considered the first-choice approach to management. However, the widespread use...Nuptial night tragedy
Case 1 A fit and well 50-year-old gentleman presents to the emergency department with pain and swelling of his penis that started a few hours after he had a shower earlier in the day. On examination, the appearance is as...Dr Glaucomflecken: Stayin’ Alive
Peter Cackett spoke to ophthalmologist and social media sensation Dr Glaucomflecken about his early days in comedy, the role satire can play in impacting medical governance, and where he might take his brand of medical comedy next. It was towards...
Underactive Bladder
This book is an excellent update on the concept of the underactive bladder. The authors and editors led by Chris Chapple address some of the controversies surrounding definitions, diagnosis and treatment. The International Continence Society (ICS) currently defines detrusor overactivity...
