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Purple urine bag syndrome

1 July 2021 | | URO - Infection, URO - Functional / Reconstructive Urology, URO - Trauma & Emergency
Purple urine bag syndrome (PUBS) is an uncommon phenomenon where the tubing and urinary catheter bag is noticed to undergo purple discolouration. This has been linked with urinary tract infections (UTI), chronic debilitated states and prolonged catheterisation. PUBS was noticed...

Focal therapies in prostate cancer

1 November 2018 | | URO - Urologic Oncology, URO - Technology
The standard of care in the management of prostate cancer has, to date, always been to treat the whole gland. This has ranged from surveillance, surgical excision / prostatectomy or external beam radiotherapy / whole gland brachytherapy. With the evolution...
European Urology journal front cover.

Oncological benefits of extended pelvic lymph node dissection

2 July 2025 | | URO - Urologic Oncology
Touijer and colleagues present extended follow-up results from a large randomised trial comparing limited pelvic lymph node dissection (l-PLND) and extended PLND (e-PLND) in prostate cancer patients undergoing radical prostatectomy. The study aimed to assess whether e-PLND, which includes external...

Update on immunotherapy for non-muscle invasive transitional cell carcinoma of the bladder

7 January 2021 | | URO - Urologic Oncology
Patients with high-risk non-muscle invasive bladder cancer (NMIBC) that have failed Bacillus Calmette-Guérin (BCG) treatment are a difficult group to treat, and many may not be suitable for the preferred treatment option of radical cystectomy. Bladder-preserving treatments for BCG-unresponsive high-risk...

Thiazide diuretic prophylaxis for kidney stones and the risk of diabetes mellitus

1 May 2015 | | URO - Endourology & Stones
Thiazide diuretics have been used to reduce calcium nephrolithiasis recurrence as it is tolerated well, inexpensive and reduces calcium excretion in urine. It has been linked with increased risk of diabetes mellitus (DM) in the presence of hypertension (ALLHAT study),...
European Urology journal front cover.

Anti-VEGF and PD-1 combinations in renal cell carcinoma

2 July 2025 | | URO - Urologic Oncology
Over the past decade, vascular endothelial growth factor (VEGF) tyrosine kinase inhibitors (TKIs) have been central to treating renal cell carcinoma (RCC), with oncologists refining dosing strategies to balance treatment efficacy with quality of life (QoL). Recently, the introduction of...

Personal productivity tools

1 March 2015 | | URO - Technology
We live in an interconnected world that is constantly striving for a share of our attention. Smartphones, tablets and wearable computers are always by our sides, with procrastination and distractions only ever one touch away. A survey by TecMark in...

Demanding cases or nightmares in endourology? Sep/Oct 2016

1 September 2016 | | URO - Endourology & Stones
In this issue the authors will present once in a career cases that can truly haunt a urologist. “Mistakes are like bad loves, the more you learn from them, the more you wish they’d never happened. “ Gregory David Roberts*...

The PROMIS trial – time for multi-parametric MRI before a first prostate biopsy

1 March 2017 | | URO - Uroradiology, URO - Urologic Oncology
Whilst the relatively random process of 12 core transrectal ultrasound guided (TRUS) prostate biopsy remains by far the most widely employed approach to prostate cancer diagnosis in the UK, its flaws as a standalone diagnostic strategy are increasingly apparent. TRUS-biopsy...

An inconvenient truth: reflections on the NHS

15 June 2023 |
“What gets us into trouble is not what we don’t know. It’s what we know for sure that just ain’t so.” The above is a quote attributed to Mark Twain from the 2006 documentary, An Inconvenient Truth, which follows Al...

A guided guide to the guide wire

6 May 2020 | | URO - Endourology & Stones, URO - Technology
The use of guide wires has become a core skill utilised by urologists, especially within the field of endourology. The authors take us through the development of the guide wire and their current use in urology. The history The first...

A negative ureteroscopy for stone disease: is it acceptable and is it avoidable?

1 September 2018 | | URO - Endourology & Stones
Urinary tract stone disease and the consequent demand for endoscopic intervention in the upper urinary tract is an increasing phenomenon [1]. Although ureteroscopy is generally considered to be associated with low morbidity [2], risks do exist. Recognised complications include urothelial...