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Prostate Cancer and Prostatic Diseases cover image.

Abiraterone acetate in men with castration-resistant prostate cancer

1 November 2017 | | URO - Urologic Oncology
With emerging results from the Stampede and Latitude studies, abiraterone has taken the forefront in the management of metastatic prostate cancer while researchers try to identify the ideal timing for administration. It is a potent inhibitor of CYP17 which results...
Prostate Cancer and Prostatic Diseases cover image.

Radium-223 treatment outcomes after multiple lines of mCRPC therapy in clinical practice: implication of pre-treatment spinal epidural disease

1 September 2017 | | URO - Urologic Oncology
There are a number of treatments now available to patients with metastatic castrate-resistant prostate cancer (mCRPC). However, the optimal timing and order in which they are given is less clear. Radium-223 was FDA-approved for mCRPC patients with symptomatic bone metastases...

COVID-19: the impact on urology so far

4 May 2020 | | URO - Core Urology
“How very little can be done under the spirit of fear.” Florence Nightingale Since 31 December 2019 when a cluster of pneumonia cases with an unknown cause were first referred to the WHO Country Office in China, there has been...

Priapism in sickle cell disease

2 March 2022 | | URO - Andrology
What is sickle cell disease? Sickle cell disease (SCD) is one of the most common single-gene disorders in the UK affecting approximately one in every 2000 live births. Approximately 20-25 million people worldwide have SCD. It predominately affects those of...

Focal therapy trials

6 November 2020 | | URO - Urologic Oncology
Men with localised prostate cancer have traditionally required whole gland treatment involving radical prostatectomy or radical radiation treatment, independent of disease location and size. Increasing evidence supports the use of active treatment only in those men diagnosed with prostate cancer...

Mentorship and its role in surgical training

6 November 2020 | | URO - Core Urology
Is there a principle which could help address multiple challenges in surgical training? One which has potential to improve recruitment and retention of staff to our specialty, quality of patient care and surgeon morale? The author discusses the past present...

Prostate cancer

1 July 2015 | | URO - Urologic Oncology
Case 1 What is prostate specific antigen (PSA) and what is its function? According to the ERSPC Trial (at 13 years), what was the number needed to screen and diagnosed to prevent one prostate cancer death and what was the...

The role of specialist therapeutic radiographers in the treatment and care of men with prostate cancer

1 March 2016 | | URO - Urologic Oncology
The Statement of Intent: Cancer Strategy for England: 2015-2020 indicates that the number of people diagnosed with cancer each year will continue to grow rapidly due to the ageing population. There is also a requirement to diagnose and offer patients...

Recent developments in bladder cancer – MIBC

5 September 2022 | | URO - Urologic Oncology
This article takes a look back over recent years at new innovations and developments relating to muscle-invasive bladder cancer (MIBC) specifically, and will also touch upon what the future may hold. This article is also written as a continuation of...

ICS updates in continence care: the role of the nurse continence specialist in continence services

1 November 2016 | | URO - Functional / Reconstructive Urology
The nurse who specialises in continence care is recognised as a key member of interdisciplinary teams seeking to deliver high quality integrated continence services. The recently published international service specifications for continence care [1] supports the use of specialist continence...

Sperm selection techniques in assisted reproductive technologies: state of the ART?

4 May 2023 | | URO - Andrology, URO - Technology
Infertility is the inability to achieve pregnancy following one year of regular, unprotected intercourse (in the fertile phase of the menstrual cycle). Infertility is a common problem that affects between 7 and 15% of couples worldwide, with male factor infertility...

Kidney stones in pregnancy

2 November 2023 | | URO - Endourology & Stones
Case 1 A 28-year-old female, 19 weeks pregnant, presents with severe left loin pain. There is no past medical history of note. Blood tests show a white cell count of 14.1x109/L and creatinine of 56umol/L. An ultrasound scan (USS) reports...