You searched for "urothelium"

87 results found

Artificial intelligence in bladder cancer diagnostics

Bladder cancer (BCa), ranking as the 10th most common cancer worldwide, poses a significant health burden with high morbidity and mortality [1]. Timely tumour detection and accurate evaluation are crucial for effective management, as the prognosis is dependent on the...

Female and functional

Case 1 A 65-year-old woman presents with an 18-month history of “recurrent urinary tract infections” (rUTI). She is otherwise fit and well with no underlying medical problems and no lower urinary tract symptoms. What is the definition of a UTI...

Intravesical glycosaminoglycan analogue instillations for recurrent cystitis

Introduction The symptoms of recurrent cystitis can be triggered by inflammatory or infective causes. Bladder pain syndrome (BPS) and bacterial recurrent lower urinary tract infection can both present with symptoms of recurrent cystitis and cause significant morbidity in affected individuals....

Tissue-based biomarkers steering clinical decisions in patients with urothelial cancer

Biomarkers play an essential role in the diagnosis and treatment of urothelial cancer (UC), with PD-L1, FGFR, and MMR proteins being the most clinically established. These biomarkers, derived from histological specimens, guide therapeutic decisions for bladder cancer (BCa) and upper...

Update on immunotherapy for non-muscle invasive transitional cell carcinoma of the bladder

Patients with high-risk non-muscle invasive bladder cancer (NMIBC) that have failed Bacillus Calmette-Guérin (BCG) treatment are a difficult group to treat, and many may not be suitable for the preferred treatment option of radical cystectomy. Bladder-preserving treatments for BCG-unresponsive high-risk...

Long-term bladder drainage: blessing or disaster in disguise

Chronic bladder dysfunction occurs in many neurologic disorders e.g. multiple sclerosis, Parkinson’s disease, stroke, etc. Suprapubic catheters (SPC) are inserted every day and every urology department has a pool of ‘difficult’ patients who keep coming back. This paper compares SPCs...

Use of bone windows in urological CT

Introduction Unenhanced computed tomography of kidneys, ureter and bladder (CTKUB) is the recommended gold standard investigation in patients with acute renal colic. CT urography is now a commonly used technique in the investigation of haematuria, for surgical planning and for...

The risk of tumour recurrence in patients undergoing renal transplantation for end-stage renal disease

End stage renal disease (ESRD) patients in need of a kidney transplant who have a previous history of urological cancer should undergo a cancer-free waiting period before receiving a kidney transplant. Currently the recommended waiting time is based on the...

Urinary frequency and COVID-19: is there a missing link?

The current COVID pandemic has been a worldwide challenge for over a year. It can affect an individual in various ways. According to the World Health Organization, the classical signs are dry cough, fever and shortness of breath. In addition,...

Urology Unboxed: A guide for aspiring urology residents

Urology Unboxed was a delightful read. It is a comprehensive guide for resident and future resident urologists who seek a structured and in-depth insight into common urological presentations. This easy-to follow handbook encompasses everything that a resident surgeon would require...

Urology: The Last Review - Rapid revision for FEBU and board exams

Urology: The Last Review is an invaluable resource for those revising for Fellow of the European Board of Urology (FEBU) and board exams. The book begins by diving into paediatric urology, with a thorough look into common congenital anomalies and...

Haematuria after transurethral resection of bladder tumour

Transurethral resection of bladder tumour (TURBT) is a common urological procedure, primarily for urothelial carcinoma, with smoking being the leading risk factor. Many patients are on antithrombotic agents (ATAs – antiplatelets or anticoagulants), which increase bleeding risks. Despite guidelines on...