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First and second-line treatments in metastatic renal cell carcinoma
Over the past two decades, the treatment landscape for metastatic renal cell carcinoma (mRCC) has evolved significantly, leading to a quadrupling of patient survival rates. Modern systemic treatments include combinations of anti-PD-1 antibodies with either anti-CTLA-4 antibodies or antiangiogenic tyrosine...Artificial penile pearls: what every Urologist should know!
Penile implants are inert objects placed beneath the skin of the penis through an incision. These are variously referred to as Yakuza beads, pearls, ball bearings, speed bumps, penile marbles, inserts, etc. The term ‘penile implant’ described here should not...Ejaculatory dysfunction: a review of current practice and guidelines
Introduction The ejaculatory process is paramount to procreation in nature. It is a complex orchestration of physiology that results in emission of the ejaculate into the posterior urethra followed by ejection of those fluids from the urethra and orgasm. The...Burnout: is this just a pandemic phenomenon?
The phrase ‘burnout’ is often heard, but what is it, and what are the early warning signs? Importantly, how can it be prevented or managed? Over the last few years, health professional wellbeing, mental health, and burnout have come to...An introduction to research governance
Research is the process of acquiring new generalisable knowledge and should be fully integrated into healthcare work. There is a growing drive to encourage and further develop evidence-based practice in medicine so that staff and patients benefit from improved healthcare...Medical statistics for urologists: part 2 – probability and hypothesis testing
Following on from Part 1 of this series (Part 3 available here), this article aims to build on other analytical techniques commonly used within medical research, focusing on simple examples. Probability and testing Before exploring hypothesis testing, it is vital...Ejaculatory dysfunction – too swift, too slow and the no-show
Timing is everything.’ Although an expression most frequently linked to comedy, timing also seems just as critical in the business of sexual climax. Indeed, many men worry about ejaculating. Too soon is embarrassing. Too slow is frustrating. And not ejaculating...Fertility Network UK: raising awareness of male infertility
Fertility Network UK are reaching out to clinicians in the urology field to raise awareness of the need to support men as the diagnosis of infertility on their emotional wellbeing and mental health can be devastating. This lack of support...‘The Rise of a Specialty’ – Exhibition at the Royal Society of Medicine
The founding of the Royal Society of Medicine’s (RSM) Urology Section 100 years ago this year was crucial to the establishment of urology as a specialty in Great Britain in its own right. To mark this anniversary, earlier this year...SMILE: sustaining medical education in a lockdown environment
2020 posed challenges to medical education like never seen before. In an effort to contain and slow the spread of coronavirus all UK medical schools ceased or reduced face-to-face contact. This sudden, and for many, unexpected change resulted in pressures...Lasers in benign prostatic hyperplasia
Clinical benign prostatic hyperplasia (BPH) impacts on the quality of life of many men. It is intimately related to ageing, but exact calculations of its prevalence remain difficult since an accurate clinical definition still eludes us. Histological BPH has been...
