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Tackling stones in children: is it difficult to crack on?
The incidence of stone disease in the paediatric population has been increasing worldwide, particularly for the adolescent age group (12–17 years of age). In this article the authors discussed the evolutions of percutaneous nephrolithotomy (PCNL) and ureteroscopy (URS) in children....
Botox® instillation into the bladder
Patients with refractory overactive bladder (OAB) may be offered OnabotulinumtoxinA (Botox®) as one of the third-line options. Given the invasive nature of requiring cystoscopy, injections via a needle and local anaesthesia, it would be simpler, more convenient and more accessible...
Smith’s Textbook of Endourology, 2 Volume Set, 4th Edition
Since the founding fathers of endourology first published this textbook in 1996, the surgical vista has been changed unrecognisably by technological advances. Laparoscopic approaches have become commonplace for renal, ureteric, bladder and prostatic surgery, and robotic-assisted techniques have developed with...
Impact of adjuvant radiation therapy on urinary continence recovery after radical prostatectomy
The functional side-effects of both radical prostatectomy and radiotherapy for prostate cancer are well known. The aim of this study was to evaluate if there was a significant worsening in recovery of urinary continence in those undergoing radical prostatectomy followed...
The importance of assessing frailty in patients prior to radical prostatectomy
This large-scale retrospective study evaluated the short-term postoperative outcomes in patients with localised prostate cancer treated with radical prostatectomy (RP). Both body mass index (BMI) and Charlson comorbidity Index (CCI) are well established indicators of adverse outcomes post major surgery,...
Cortical stimulation for voiding dysfunction in multiple sclerosis
Voiding dysfunction (VD) increases morbidity in patients with multiple sclerosis (MS), and may be associated with urinary tract infections, stones and renal failure. Catheterisation is required when impaired hand function precludes self-catheterisation, which is associated with further morbidity. In this...
PARP inhibitors and prostate cancer
The discovery that BRCA1/2-deficient tumour cells are highly sensitive to poly-ADP ribose polymerase (PARP) inhibitors (PARPi) established the foundation of synthetic lethality in metastatic castration-resistant prostate cancer (mCRPC). The TOPARP-A trial confirmed clinical benefit, with PARPi activity largely restricted to...
Has laparoscopic radical prostatectomy had its day?
Over recent years there has been a massive uptake in robotic surgery particularly for robot-assisted prostatectomy. The drive for this has been patient and physician led with little in the way of prospective randomised trials showing benefits over established operative...In conversation with Tamsin Greenwell
We were delighted to chat with Tamsin Greenwell, Consultant Urological Surgeon at University College London Hospital and Chair of the United Kingdom Continence Society. Can you tell us a little bit about what attracted you to the field of urology...Surgical risk prediction
Patients presenting for urological surgery range from the young and fit to the elderly with multiple, and often significant, coexistent diseases. This latter cohort can present a significant challenge in the perioperative period, sometimes irrespective of the type of surgery....Edward Canny Ryall: the lost urologist
In this series of articles I am going to show you some of the exhibits contained in the BAUS Virtual Museum of the History of Urology which is part of the BAUS website (www.baus.org.uk). In the last article we looked...
