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Increasing PSA after negative prostate biopsy - solving the clinical puzzle

There are standard guidelines for first transrectal ultrasonography (TRUS) guided biopsy in a patient presenting with elevated prostate-specific antigen (PSA) or suspicious digital rectal examination (DRE) findings. Patients are generally warned before a TRUS biopsy in respect of a false...

Malignant upper urinary tract obstruction: emergency presentations and long-term outcomes

Malignant upper urinary tract obstruction (MUUTO) is a frequent emergency urological referral, often necessitating kidney drainage to preserve renal function. However, many patients have advanced cancer with limited life expectancy, raising questions about intervention benefits. While percutaneous nephrostomy (PCN) or...

Prostatic artery embolisation – an option for select BPO patients

Few proponents of prostatic artery embolisation (PAE) regard it as a potential standard in future for benign prostatic obstruction (BPO) / benign prostatic hyperplasia (BPH) treatment. Present guidelines from the National Institute for Health & Care Excellence (NICE) and the...

Scalpels and stunts: reflections from an academic trainee and international-level athlete

When people find out I’m a urology registrar, they usually nod politely or giggle for obvious reasons. When they find out I’m also a competitive cheerleader, they tend to blink, pause, and then ask: “Wait, like pom-poms and high kicks?”...

Phlebotomists, Nurses & HCAs required – Scotland

Following the launch of a groundbreaking joint initiative between EDX Medical and The Graham Fulford Charitable Trust, we will be delivering up to 25,000 prostate cancer risk tests across Scotland throughout the remainder of 2026. To support this important programme,...

Richard Wolf Range Update

Richard Wolf a global business with headquarters in Germany and over a century of tradition and expertise in the field of endoscopy. We develop, manufacture and market specific system solutions for minimally invasive human medicine.

Comparison of pathological stage in patients treated with and without neoadjuvant chemotherapy for high-risk UTUC

High-risk upper tract urothelial carcinoma (UTUC) has been associated with poor survival outcomes. The authors evaluated the role of neoadjuvant chemotherapy in high-risk cases prior to radical nephroureterectomy (RNU) in terms of pathological stage of the final surgical specimen. A...

The assessment and medical treatment of LUTS secondary to BPH

The term benign prostatic hyperplasia (BPH) describes prostate enlargement due to non-cancerous processes. Several aetiological mechanisms are involved, including hormonal and vascular alterations; abnormal regulation of apoptosis; and prostatic inflammation, which may stimulate cellular proliferation. With ageing, prostate enlargement can...

Kidney stones in pregnancy

Urolithiasis related complications are estimated to affect between 1:200 and 1:2000 pregnancies [1,2]. With around 825,000 conceptions in England and Wales in 2021 [3], this represents an uncommon but not rare occurrence. What is normally a straightforward pathway for a...

BJUI Knowledge

BJUI Knowledge is a new online educational platform for urologists. It combines online Continuing Professional Development (CPD) through e-learning, with a platform for recording CPD activity. It was released in February 2016 and is free to access and use for...

Hypercalciuria in children with monosymptomatic nocturnal enuresis

Nocturnal enuresis, defined as intermittent urinary incontinence, regardless of the presence or absence of daytime symptoms, is common. Monosymptomatic nocturnal enuresis – MSNE (no daytime symptoms) has four main causes identified with it: poor vasopressin action, nocturnal polyuria, poor arousal...

Performance status may alter outcomes in those treated with abiraterone

The drug therapies available for those with metastatic castrate-resistant prostate cancer have increased over the past few years. Abiraterone, a CYP17 inhibitor, has been proven effective in phase three trials, however those with poor performance status were largely under-represented in...