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Anti-VEGF and PD-1 combinations in renal cell carcinoma
Over the past decade, vascular endothelial growth factor (VEGF) tyrosine kinase inhibitors (TKIs) have been central to treating renal cell carcinoma (RCC), with oncologists refining dosing strategies to balance treatment efficacy with quality of life (QoL). Recently, the introduction of...
Campbell-Walsh Urology 11th Edition Review, 2nd Edition
Available separately to the four-volume Campbell-Walsh Urology (11th edition), is this Review edition. The hard copy appears substantial and roughly the same size as the other volumes, and is perhaps best considered the final volume and test of knowledge acquisition...Nonacus Clinical Services announce partnership with The London Clinic to deliver GALEAS™ Bladder test
Nonacus Clinical Services, the UK laboratory delivering genomic cancer testing services to the NHS and private healthcare providers, recently announced it is working with The London Clinic to help more patients benefit from its non-invasive GALEAS™ Bladder test for cancer....Use of MRI in the evaluation of prostate cancer: part 1
Introduction Prostate cancer remains the most commonly diagnosed cancer in males and the second leading cause of cancer related deaths in UK men, after lung cancer [1]. The incidence of prostate cancer in the UK has shown a rapid increase...MRI screening for prostate cancer: a step towards a ‘prostagram’
The UK National Screening Committee has been calling for further research into alternative screening tests for prostate cancer. The committee decided against prostate cancer screening using prostate specific antigen (PSA) testing on the basis that “PSA is still a poor...
Scientific Advances in Reconstructive Urology and Tissue Engineering
Scientific Advances in Reconstructive Urology and Tissue Engineering stands as a beacon in the field, providing a comprehensive exploration of cutting-edge developments in the intersection of reconstructive urology and tissue engineering. Edited by Matthias D Hofer, this paperback edition comprises...The effect of COVID-19 on urology training
COVID-19 has affected all aspects of medicine. Urologists have been called upon to work in vastly different working environments including acute pan-surgical teams, intensive care and medical wards. The strategies put in place by hospital management teams vary significantly across...
Curing pure CIS with radical surgery: lessons learned
As carcinoma in situ (CIS) theoretically has no ability to invade or metastasise, performing radical cystectomy for CIS-only disease should be curative. In this single centre review over 37 years, 1964 patients undergoing cystectomy were analysed with 52 undergoing surgery...
Intravesical cytosine arabinoside + Mitomycin C for bladder cancer – is it beneficial?
Mitomycin C (MMC) is often used as an intravesical therapy for low / intermediate risk non-muscle invasive bladder cancer. This randomised controlled trial (RCT) was designed to assess the safety and efficacy of MMC + cytosine arabinoside (Ara-C). Ara-C was...
Outcomes of sarcomatoid differentiation in urothelial carcinoma
Sarcomatoid differentiation is a rare variant of urothelial carcinoma (UC) seen in 0.6% of cases. Its response to neo-adjuvant chemotherapy (NAC) has not been well reported. The authors have done a retrospective analysis of patients undergoing cystectomy between 1995 and...COVID-19: the impact on a junior registrar
Prior to the coronavirus pandemic I was a trust grade junior registrar, using this year at a district general hospital to gain experience, skills and portfolio points for round two of National Selection. My urology registrar on-call duties would consist...
