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Adjuvant radiotherapy versus wait-and-see after radical prostatectomy

1 September 2014 | | URO - Urologic Oncology
Optimum treatment modalities in prostate cancer continue to evolve, with debates at each stage of the evolution process, from focal therapy to radical treatment. In this randomised study, Wiegel et al. investigated the role of adjuvant radiotherapy following open radical...

The EP2 receptor – a novel target for prostate cancer?

1 July 2014 | | URO - Basic Science Research, URO - Urologic Oncology
This basic science paper sets out to evaluate the effects that celecoxib, a selective cyclo-oxygenase-2 (COX-2) inhibitor, have on prostate cancer cell lines and evaluated the mechanisms behind these effects. COX-2 induces the production of prostaglandins, which promote cell proliferation...

Comparative effectiveness of nephron sparing surgery vs ablation

1 May 2014 | | URO - Urologic Oncology
Nephron sparing surgery (NSS) and minimally invasive modality of thermal ablation have attracted great attention as an alternative surgical treatment to radical nephrectomy (RN) for renal tumours <4cm. High quality evidence comparing disease specific survival (DSS) is lacking. This issue...
World Journal of Urology cover image.

Save the orchid

3 February 2023 | | URO - Functional / Reconstructive Urology, URO - Urologic Oncology
In many urological cancers there is currently more and more inclination for organ-preserving surgery but in patients with germ cell tumours (GCT), radical orchidectomy remains the gold standard. Can we somehow save the testes? This study aims to summarise published...

Artificial intelligence in bladder cancer diagnostics

2 May 2025 | | URO - Urologic Oncology
Bladder cancer (BCa), ranking as the 10th most common cancer worldwide, poses a significant health burden with high morbidity and mortality [1]. Timely tumour detection and accurate evaluation are crucial for effective management, as the prognosis is dependent on the...

What is the role of evidence-based medicine in urology?

1 March 2016 | | URO - Basic Science Research
The concept of ‘evidence-based medicine’ (EBM) was first developed in the early 1990s and was described as “the conscientious, explicit and judicious use of the current best evidence in making decisions about the care of individual patients” by the recently...

Image-guided renal cryoablation

1 November 2014 | | URO - Urologic Oncology, URO - Uroradiology
Introduction There has undoubtedly been a dramatic increase in the number of patients diagnosed with small renal masses in recent years [1]. The rapidly expanding use of CT has led to a large number of incidental diagnoses, but increasing longevity...

Using change theories can help nurses implement better care in prostate cancer

6 November 2024 | | URO - Urologic Oncology
Nurses can help support change in prostate cancer care by understanding change management and models and provide leadership in improving prostate cancer care. An important part of being able to lead change is to understand change theories such as the...

Demanding cases or nightmares in uro-oncology? Sep/Oct 2021

3 September 2021 | | URO - Urologic Oncology
Active surveillance for prostate cancer: missing the boat Case In 2005 a 43-year-old man of Afro-Caribbean ethnicity was referred to our centre for investigation of suspected prostate cancer. Digital rectal exam revealed a firm right lobe, PSA of 2.3ng/ml, prostate...

Infections and inflammation: Part 1

1 November 2018 | URO - Infection
See also Part 2 and Part 3. Case 1 A 59-year-old man presented with right loin pain. His GP arranged for him to have an intravenous urogram (IVU) and subsequent CT urogram performed. What is the likely diagnosis? What are...

Does empowering men on active surveillance for prostate cancer improve patient compliance and reduce conversion to treatment?

4 November 2025 | | URO - Core Urology, URO - Urologic Oncology
Active surveillance is a major treatment option for patients with favourable prognosis prostate cancer, such as those regarded as Cambridge Prognostic Group (CPG) 1 and 2 [1]. The rationale for this management strategy is the lack of survival benefit from...

Non-urothelial bladder malignancies

3 May 2024 | | URO - Urologic Oncology
Case 1 An 80-year-old gentleman presented with a history of visible haematuria and recurrent urinary tract infections (UTIs). He has been performing intermittent self catheterisation (ISC) for detrusor underactivity for over 20 years. A flexible cystoscopy showed these appearances of...