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Comparative effectiveness of nephron sparing surgery vs ablation
Nephron sparing surgery (NSS) and minimally invasive modality of thermal ablation have attracted great attention as an alternative surgical treatment to radical nephrectomy (RN) for renal tumours <4cm. High quality evidence comparing disease specific survival (DSS) is lacking. This issue...
Can PET/CT help in selecting treatment for patients with muscle-invasive bladder cancer more appropriately?
Radical cystectomy is one of the most drastic procedures that urological patients have to undergo with a five-year mortality of around 50% in those with organ-confined disease at presentation. Traditional imaging is with contrast-enhanced computed tomography (CT) but lymphadenectomy often...
A phase II dose-ranging study of mirabegron in patients with OAB
This was a multinational, multicentre, randomised, double–blind, double-dummy, parallel group placebo- and active- controlled phase II study. The study enrolled 1108 men and women aged 18 and over. The criteria were: patients must have had overactive blader (OAB) symptoms for...
Supranormal function on MAG-3 – what is its significance and how to predict?
Differential renal function (DRF) on MAG-3 scans is typically used in patients with pelvic ureteric junction obstruction (PUJ obstruction). Supranormal DRF is when the kidney with PUJO has higher DRF than the normal contralateral kidney. The authors in this study...
Testosterone supplementation after prostatectomy – journey from bad to good
The role of androgens in the pathogenesis of prostate cancer is quite complex and is not entirely clear yet. Despite several reports suggesting testosterone use is safe in patients diagnosed with prostate cancer, many clinicians are still reluctant to use...
Homo digitalis during COVID-19?
The COVID-19 pandemic has affected all aspects of our lives. We have seen huge changes in the health service, medical practice and hospital working. Many urology meetings – national and international – were cancelled and seminars and courses have become...
BCG after TURBT – does timing matter?
Intravesical bacille Calmette–Guerin (BCG) therapy continues to be widely used for patients with intermediate / high-risk non-muscle invasive bladder cancer (NMIBC). In this article, the researchers identified the lack of sufficient evidence with regards to timing of BCG after transurethral...
PIRADS-3 lesions and clinically significant prostate cancer – what are we missing?
The use of pre-biopsy MRI has definitely enhanced our decision making in managing patients with suspected prostate cancer (PCa). There is still uncertainty around the outcomes for patients with PIRADS-3 lesions, with a small but definite risk of missing clinically...BAUS Annual Scientific Meeting 2023
Day 1 Highlights by: Omer Abdalla, Urology ST6 - Wirral University Teaching Hospitals, Mersey BSoT Trainee's rep (@Omer_Uro1). BAUS 2023 began last night with a wonderful welcome reception at the Birmingham Library, where urologists from throughout the UK met again,...Our experience: from London and Glasgow urology, to the world down under
In November 2023, we were privileged to have been hosted at the Urological Society of Australia and New Zealand’s (USANZ) annual trainee week in the beautiful city of Adelaide, South Australia. Each year, USANZ organises a week for their local...Klinefelter’s syndrome
Klinefelter’s syndrome (KF) is the most frequent sex chromosome abnormality with an estimated prevalence of 1 in 500 to 1 in 700 newborn males and 1 in 10 in men with azoospermia. While the majority of cases are an XXY...
