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Men with a susceptibility to prostate cancer: implications of ethnicity in PCa risk-prediction and diagnosis

5 January 2022 | | URO - Urologic Oncology
The diagnostic and therapeutic landscapes of prostate cancer (PCa) have advanced at great pace in the past decade. However, disparities in access to care, clinical outcomes and representation in therapeutic, interventional and genomic studies continue to exist between Afro-Caribbean (AC)...

Benign prostatic hyperplasia: what are the benefits and harms of various surgical management options?

9 March 2020 | | URO - Functional / Reconstructive Urology, URO - Infection, URO - Neurourology, URO - Technology
Benign prostatic hyperplasia (BPH) is characterised by stromal and epithelial prostatic cell hyperplasia. The enlarged prostate may be associated with voiding and storage lower urinary tract symptoms (LUTS). These have been predominantly attributed to bladder outlet obstruction (BOO), assumed to...

Testicular microlithiasis

1 May 2015 | | URO - Urologic Oncology, URO - Uroradiology
Introduction Testicular microlithiasis (TML) was originally described in 1970 in a healthy four-year-old boy [1] and the first paper regarding microlithiasis as an entity seen on ultrasound was published in 1987 [2]. Testicular microlithiasis is seen on ultrasound as small,...

Paediatric urology: what you need to know for FRCS (Urol)

4 March 2025 | | URO - Paediatric Urology
Lianne Pickett, Urology ST5 at Great Ormond Street Hospital (GOSH), and Ms Neetu Kumar, Consultant Paediatric Urological Surgeon at GOSH, provide expert insights into the key aspects of paediatric urology. Curriculum Paediatric urology contributes one of the eight stations of...

SUSPEND suspended MET

1 July 2015 | | URO - Endourology & Stones
This review is on the recent groundbreaking evidence on medical expulsive therapy (MET). MET using alpha adrenergic blockers (like tamsulosin) are in regular clinical practice. Even though it is an off label prescription, it is well accepted and practised world...
European Urology journal front cover.

Tissue-based biomarkers steering clinical decisions in patients with urothelial cancer

2 July 2025 | | URO - Urologic Oncology
Biomarkers play an essential role in the diagnosis and treatment of urothelial cancer (UC), with PD-L1, FGFR, and MMR proteins being the most clinically established. These biomarkers, derived from histological specimens, guide therapeutic decisions for bladder cancer (BCa) and upper...
European Urology journal front cover.

Are standard repeat biopsies during active surveillance for prostate cancer still necessary?

2 July 2025 | | URO - Urologic Oncology
Active surveillance (AS) has emerged as a key strategy for managing low-risk prostate cancer (PCa), offering an alternative to immediate treatment. Initially, AS relied on prostate specific antigen (PSA) testing, digital rectal examinations (DRE), and systematic biopsies. Early studies using...

Thermal ablative techniques for small renal masses

1 July 2017 | | URO - Urologic Oncology, URO - Technology
The incidence of renal cell carcinoma has increased over the past decade which can be partly attributed to the increased use of imaging modalities [1,2]. Nephron sparing procedures for the management of small renal tumours have gained popularity which include...

Complications of CISC

1 July 2014 | | URO - Infection, URO - Functional / Reconstructive Urology, URO - Neurourology
Introduction Clean intermittent self catheterisation (CISC) was first introduced and popularised by Lapides in 1972. Since then its utilisation has become widespread and it is now commonly used throughout the world as the preferred means of facilitating complete and effective...

Visual-estimation (cognitive), image-fusion (software) and in-bore targeted prostate biopsy: is there an optimal approach?

3 March 2021 | | URO - Urologic Oncology, URO - Technology
The diagnostic superiority of multiparametric magnetic resonance imaging (mpMRI) prior to targeted and systematic prostate biopsy over systematic transrectal ultrasound-guided (TRUS) biopsy alone in the detection of clinically significant prostate cancer (csPCa) has been proven by multiple level 1 studies...

Men with a susceptibility to prostate cancer: implications of family history in PCa risk-prediction

3 September 2021 | | URO - Urologic Oncology
Incorporation of family history (FH) status into prostate cancer (PCa) risk stratification has the potential to underpin many aspects of PCa care. This group of men presents a unique challenge in early cancer detection, particularly given that most men without...

Retroperitoneal sepsis

1 September 2016 | | URO - Infection
Case 1 An 80-year-old woman presented with history of recurrent and recent cystitis, low grade pyrexia, abdominal and back pain, and pain on movement of the left hip which was observed to be flexed and externally rotated. What is the...