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Recent developments in bladder cancer – MIBC

5 September 2022 | | URO - Urologic Oncology
This article takes a look back over recent years at new innovations and developments relating to muscle-invasive bladder cancer (MIBC) specifically, and will also touch upon what the future may hold. This article is also written as a continuation of...

Surgery in disorders of sexual development with gender issues

1 March 2017 | | URO - Andrology, URO - Paediatric Urology
After the initial consensus meeting of 10 years ago on disorders of sex development (DSD) with the introduction of the new terminology and classification there are still abundant controversial issues associated with the management of children with these conditions. This...

BCG strain differences have an impact on clinical outcome in bladder cancer immunotherapy

1 March 2015 | | URO - Urologic Oncology
Bacillus Calmette-Guérin (BCG) has been part of the treatment algorithm for non-muscle invasive bladder cancer (NMIBC) for a number of years. In this single centre, prospective, randomised trial, two of the most commonly available strains, BCG Connaught and BCG Tice,...

Adjuvant radiotherapy versus wait-and-see after radical prostatectomy

1 September 2014 | | URO - Urologic Oncology
Optimum treatment modalities in prostate cancer continue to evolve, with debates at each stage of the evolution process, from focal therapy to radical treatment. In this randomised study, Wiegel et al. investigated the role of adjuvant radiotherapy following open radical...

The EP2 receptor – a novel target for prostate cancer?

1 July 2014 | | URO - Basic Science Research, URO - Urologic Oncology
This basic science paper sets out to evaluate the effects that celecoxib, a selective cyclo-oxygenase-2 (COX-2) inhibitor, have on prostate cancer cell lines and evaluated the mechanisms behind these effects. COX-2 induces the production of prostaglandins, which promote cell proliferation...

What is new in lasers for endourology: looking into the future

7 January 2021 | | URO - Endourology & Stones, URO - Technology
From the first cystoscopic argon and neodymium-YAG (yttrium-aluminium-garnet) laser used for bladder tumours in 1976 by Staehler et al. [1], lasers have proven to be a versatile and an evolving tool in the therapeutic management of a variety of urological...

Understanding Stauffer’s syndrome

1 May 2018 | | URO - Andrology, URO - Basic Science Research, URO - Endourology & Stones, URO - Functional / Reconstructive Urology, URO - Infection, URO - Neurourology, URO - Paediatric Urology, URO - Technology, URO - Trauma & Emergency, URO - Urologic Oncology, URO - Uroradiology
Who was Stauffer and what is Stauffer’s syndrome? Maurice Stauffer (1915-1994) was a gastroenterologist at the Mayo Clinic in Rochester, United States, and in 1961 first characterised the non-metastatic, paraneoplastic effects of renal cell carcinoma (RCC) on liver size and...

History of prostate biopsy – part 1

1 January 2018 | | URO - Basic Science Research, URO - Urologic Oncology, URO - Technology
Part 2 of this topic is available here. Prostate biopsy (PBx) to exclude cancer has been part of clinical practice since the beginning of the 20th Century. PBx techniques have evolved over time to optimally address some of the unique...

The PROMIS trial – time for multi-parametric MRI before a first prostate biopsy

1 March 2017 | | URO - Uroradiology, URO - Urologic Oncology
Whilst the relatively random process of 12 core transrectal ultrasound guided (TRUS) prostate biopsy remains by far the most widely employed approach to prostate cancer diagnosis in the UK, its flaws as a standalone diagnostic strategy are increasingly apparent. TRUS-biopsy...

FRCS – the long way round

13 March 2023 | | URO - Technology
In this series of articles I am going to show you some of the exhibits contained in the Museum of Urology, hosted on the BAUS website (www.baus.org.uk). This month I am joined by my friend and fellow member of the...

How to conduct an endoscopic séance

1 September 2016 | | URO - Endourology & Stones, URO - Functional / Reconstructive Urology, URO - Technology
In this series of articles I am going to show you some of the exhibits contained in the Museum of Urology, hosted on the BAUS website (www.baus.org.uk). In the last article I agreed to tell you how to conduct an...

An MA in medical education – is it for you?

1 March 2015 | | URO - Andrology, URO - Basic Science Research, URO - Endourology & Stones, URO - Infection, URO - Neurourology, URO - Paediatric Urology, URO - Functional / Reconstructive Urology, URO - Technology, URO - Trauma & Emergency, URO - Urologic Oncology, URO - Uroradiology
I have recently completed a three-year MA in medical education at the University of Winchester, which has been an edifying experience. The following article may appeal to readers who are considering such a venture. I have been a consultant for...