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European Urology journal front cover.

The case against omitting systematic biopsy in younger men

7 January 2026 | | URO - Urologic Oncology
In this issue of European Urology, Al-Monajjed et al. report findings from the PROBASE trial, which evaluated prostate cancer (PC) detection in men aged 45–50 years with PSA ≥3ng/ml using both MRI-targeted biopsy (TBx) and systematic biopsy (SBx). Among 525...

RSM: Trauma and On-call Urology

16 October 2026
Why attend? Hear from leading experts in urology, trauma surgery and urgent care, including Professor David Nott OBE on trauma in hostile environments, Mr Paul Anderson on urethral trauma and reconstruction, and Charlotte Aston, Director of the GIRFT Urgent and...
European Urology journal front cover.

PARP inhibitors and prostate cancer

12 August 2026 | | URO - Basic Science Research, URO - Urologic Oncology
The discovery that BRCA1/2-deficient tumour cells are highly sensitive to poly-ADP ribose polymerase (PARP) inhibitors (PARPi) established the foundation of synthetic lethality in metastatic castration-resistant prostate cancer (mCRPC). The TOPARP-A trial confirmed clinical benefit, with PARPi activity largely restricted to...

An algorithm for the management of haemorrhagic cystitis

1 September 2015 | | URO - Endourology & Stones, URO - Functional / Reconstructive Urology, URO - Urologic Oncology
Haemorrhagic cystitis (HC) can be one of the most difficult conditions to treat in urological practice. It is characterised by intractable bleeding from the bladder and may be acute or chronic. The most frequently reported causal factors are radiotherapy (RT)...

Clinical trials 1

1 January 2017 | URO - Basic Science Research
Clinical Trials 2 is available here. Case 1 1. What are the levels of clinical evidence based on the 2009 definitions from the ‘Oxford CEBM’? 2. What is the null hypothesis? 3. What are type 1 and type 2 errors?...

Ejaculatory dysfunction: a review of current practice and guidelines

1 January 2015 | | URO - Andrology
Introduction The ejaculatory process is paramount to procreation in nature. It is a complex orchestration of physiology that results in emission of the ejaculate into the posterior urethra followed by ejection of those fluids from the urethra and orgasm. The...

Initial impressions of urology in the UK from overseas trainees

3 September 2021 | | URO - Core Urology
Readers of Urology News will be familiar with descriptions of overseas visits by UK-based urological trainees, but it is sometimes beneficial to reflect on the experience of international medical graduates (IMGs) who elect to come to work and train in...

Endoscopic management of upper tract urothelial carcinoma

1 January 2014 | | URO - Urologic Oncology
Upper tract urothelial carcinoma (UTUC) is a rare disease accounting for 5-10% of all urothelial carcinomas and has an annual incidence in Western countries of 1-2 per 100,000 [1,2]. It occurs more commonly in the pelvicalyceal system as opposed to...

Focal therapies in prostate cancer

1 November 2018 | | URO - Urologic Oncology, URO - Technology
The standard of care in the management of prostate cancer has, to date, always been to treat the whole gland. This has ranged from surveillance, surgical excision / prostatectomy or external beam radiotherapy / whole gland brachytherapy. With the evolution...

An overview of non-surgical treatment options for Peyronie’s disease

3 May 2022 |
Peyronie’s disease (PD) is a therapeutic challenge despite the availability of several non-surgical and surgical options. Very few of these options are supported by good quality evidence according to the current American and European guidelines [1-3]. The period of plaque...

First-of-its-kind international study launches to revolutionise quality of life for Black men with prostate cancer

24 August 2026
BALANCE will generate pioneering evidence to fill gaps in our understanding of the challenges Black men face with prostate cancer and the support they need, making changes possible which will improve Black men's quality of life while navigating the disease....

The impact of FGM on the genitourinary system: a 2021 perspective

3 March 2021 | | URO - Functional / Reconstructive Urology, URO - Trauma & Emergency
Awareness of female genital mutilation (FGM) in European countries has increased over recent decades as a result of globalisation and migration of populations. The World Health Organization (WHO) describes FGM as procedures that involve partial or total removal of the...