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PDE5I in LUTS – how do they work – no proof yet
Phosphodiesterase type 5 (PDE5) inhibitors used in erectile dysfunction (ED) have been shown to improve lower urinary tract symptoms (LUTS) as well. The mechanism is not well understood. One of the hypotheses for benign prostatic hyperplasia (BPH) – LUTS is...
Is routine renal tumour biopsy associated with lower rates of benign histology following nephrectomy for small renal masses?
There has been a considerable increase in the detection of small renal masses (SRM). Approximately 20% of these turn out to be benign lesions on final histopathological analysis. Therefore upfront surgery can be overtreatment in such a group of patients....
Prostate cancer mortality among elderly men after discontinuing organised screening
This study presents ground-breaking insights into discontinuing prostate cancer (PCa) screening in previously screened elderly men, aiming to mitigate the risk of overdiagnosis and overtreatment in the face of other-cause mortality. Examining men aged 70–74 who had undergone prostate specific...
Prostate cancer and an electronic nose
So far the transrectal ultrasound guided (TRUS) biopsy has been the ‘gold standard’ for diagnosing prostate cancer. However, it is invasive and can lead to complications, so there is a need for new non-invasive diagnostic tools to avoid unnecessary biopsy...
Upper tract urothelial carcinoma following cystectomy
Metachronous upper tract urothelial cancer (UTUC) is encountered in about 5% of patients after radical cystectomy (RC) with a median time to diagnosis of 24-36 months after RC, and most are asymptomatic and detected by surveillance protocols. In this multivariate...
Nocturia: the debate goes on
This study is from Ghent, Belgium. Nocturia is one of the most bothersome lower urinary tract symptoms affecting both men and women. Key factors to consider in evaluating are nocturnal polyuria (NP) and reduced bladder capacity. NP with low osmolality...
Morbidity and mortality after surgery for LUTS
The market for bladder outflow obstruction surgery is currently wide open with new technologies such as Urolift® emerging. One of the key selling points of new technologies is the comparative safety and efficacy compared to traditional techniques such as transurethral...
Laparoscopic transposition of renal lower pole crossing vessels
The vascular hitch procedure for pelvi-ureteric junction obstruction (PUJO) was initially described by Hellstroem in1951 and has become popular again since the introduction of laparoscopy. There is still much controversy as to its efficiency. The authors of this paper analyse...
HPV prevalence in invasive penile cancer and association with clinical outcome
Penile cancer risks can be increased by a number of causes such as smoking, phimosis, poor hygiene, multiple sexual partners and history of gential warts or other sexually transmitted diseases. It has been found that circumcised men have a lower...
Impact of adjuvant radiation therapy on urinary continence recovery after radical prostatectomy
The functional side-effects of both radical prostatectomy and radiotherapy for prostate cancer are well known. The aim of this study was to evaluate if there was a significant worsening in recovery of urinary continence in those undergoing radical prostatectomy followed...
Local tumour bed recurrence following partial nephrectomy
In this interesting retrospective study, the authors looked at the incidence of local tumour bed recurrence after partial nephrectomy (PN), the factors associated with that, and the management. A total of 2,271 patients’ charts were reviewed who underwent partial nephrectomies...
