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Low dose PDE5I in IC
This is a randomised, double-blind, placebo-controlled trial to evaluate the efficacy of daily low-dose sildenafil (25mg) for the treatment of non-ulcer interstitial cystitis (IC) in women. Forty-eight women with clinical diagnosis of IC, from three centres, were equally randomised to...
Abiraterone plus prednisone in metastatic, castration-sensitive prostate cancer
Abiraterone acetate, the prodrug of abiraterone, blocks endogenous androgen synthesis by inhibiting cytochrome p-450c17, a critical enzyme in androgen biosynthesis. Its active D4A metabolite also has anti-tumour effects through possibly multiple mechanisms. 3-5% of men diagnosed with prostate cancer in...
Scrotal antegrade sclerotherapy for the adolescent varicocele
The incidence of varicocele in adolescent males is around 15%. Treatment indications include symptoms (pain) and evidence of a smaller testis. Numerous surgical techniques are described but there is a lack of randomised controlled trials (RCT), specifically in adolescents. This...PROSPACKS supports prostate cancer patients starting treatment in Scotland
Men across Scotland undergoing treatment for prostate cancer can benefit from new care and support packs thanks to a project by charity Prostate Scotland and long-term funder, the Grand Lodge of Scotland. PROSPACKS – tailored packs for men beginning radiotherapy,...Two blue pills
In this series of articles I am going to show you some of the exhibits contained in the Museum of Urology, hosted on the BAUS website (www.baus.org.uk). If I were to say to you, ‘The Blue Pill’ I suspect you...
Morbidity and mortality after surgery for LUTS
The market for bladder outflow obstruction surgery is currently wide open with new technologies such as Urolift® emerging. One of the key selling points of new technologies is the comparative safety and efficacy compared to traditional techniques such as transurethral...The master’s degree in urology – a personal perspective
I have recently completed a master’s degree in urology, based jointly with the University of Edinburgh and the Royal College of Surgeons of Edinburgh. I began the course three months after commencing ST3 in urology. I had begun exploring the...Can we make LATE-presenting posterior urethral valves an EARLIER-treated condition?
What are posterior urethral valves? Posterior urethral valve (PUV) is the most common cause of congenital bladder outlet obstruction (BOO) and renal failure in male children. They were first described by the Italian anatomist Giovanni Battista Morgagni back in the...David Newman
In this series of articles I am going to show you some of the exhibits contained in the Museum of Urology, hosted on the BAUS website (www.baus.org.uk). In the last article I said I would write on a Scottish theme...
