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Increasing PSA after negative prostate biopsy - solving the clinical puzzle

There are standard guidelines for first transrectal ultrasonography (TRUS) guided biopsy in a patient presenting with elevated prostate-specific antigen (PSA) or suspicious digital rectal examination (DRE) findings. Patients are generally warned before a TRUS biopsy in respect of a false...

Prostatic artery embolisation – an option for select BPO patients

Few proponents of prostatic artery embolisation (PAE) regard it as a potential standard in future for benign prostatic obstruction (BPO) / benign prostatic hyperplasia (BPH) treatment. Present guidelines from the National Institute for Health & Care Excellence (NICE) and the...

Update on immunotherapy for non-muscle invasive transitional cell carcinoma of the bladder

Patients with high-risk non-muscle invasive bladder cancer (NMIBC) that have failed Bacillus Calmette-Guérin (BCG) treatment are a difficult group to treat, and many may not be suitable for the preferred treatment option of radical cystectomy. Bladder-preserving treatments for BCG-unresponsive high-risk...

Frailty in urology – part 2

The first article in this series defined frailty and introduced the concept and importance of identifying patients living with frailty who undergo surgery, including those undergoing urological procedures. In the second part of this series we outline how to identify...

The 5-Minute Urology Consult (Third Edition)

I suspect that if Dominic Corrigan (famous for the metaphorical escape route afforded to busy clinicians) was a urologist he would most certainly have had a copy of the The 5-Minute Urology Consult and would have then subsequently been famous...

Bladder cancer

Case 1 A 78-year-old female presents with a week history of painless haematuria. She’s a smoker and used to work in the textiles industry. She underwent a flexible cystoscopy. What does this image show? What are the two-week wait National...

An update on mobile apps in urology

Amongst the plethora of mobile applications, there are some essential applications for practising urologists, urologists in training and patients. In this month’s digital review, we highlight some essential applications. Mobile office apps Maintaining a virtual office is key to keeping...

The conservative assessment and treatment of mixed urinary and anal incontinence in women: a multidisciplinary approach

Mixed urinary incontinence Urinary incontinence (UI) is considered to be a highly prevalent condition; however, depending upon the definitions used, actual reported prevalence rates can vary significantly. The International Consultation on Incontinence (ICI) review [1], reported unadjusted prevalence estimates for...

Treatment of varicocele in children and adolescents

Varicocele occur in about 15% of all adolescents. These authors searched Medline, Embase and a number of platforms reporting on varicoses in children and adolescents, including only randomised controlled trials with patients under 21 years. After an initial 198 studies...

Adults are just big kids: a paediatric surgeon’s experience in adult urology

As an ST8 trainee in paediatric general surgery and urology, I had firmly decided on subspecialisation in paediatric urology. Whilst preparing for the dreaded final Annual Review of Competency Progression (ARCP), the all-important question of “What next?” came to the...

New drug hope for prostate cancer patients

• Hormone therapy is used to slow the progression of advanced prostate cancer, but cancers often develop resistance and continue to grow.• Research reveals that patients with higher levels of heat shock proteins have worse outcomes.• Targeting these proteins with...

APAM (Association of Physicians of Great Britain and Ireland) 118th Annual Meeting 2025

Welcome to APAM 2025 - What Awaits? APAM 2025, the 118th Annual Meeting of the AoPGBI, will take place on 3–4 April 2025 at the Royal College of Physicians in London. This prestigious event will bring together leading clinicians, researchers,...