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Prostate cancer in men of African heritage: understanding the risk and prognostic factors

Prostate cancer (PCa) represents a major public health concern and is recognised as one of the most common cancers worldwide, accounting for a significant proportion of cancer-related deaths. It is the second most common malignancy among men globally after lung...

Recent advances in the management of castration resistant prostate cancer

Castrate resistant prostate cancer (CRPC) is defined by disease progression despite androgen-deprivation therapy lowering testosterone to castrate levels. It may present as a rise in serum levels of prostate specific antigen (PSA), progression of pre-existing disease, or the appearance of...

Which kidney to remove? – The urine separator

In this series of articles, I am going to show you some of the exhibits contained in the Museum of Urology, hosted on the BAUS website (www.baus.org.uk) this time helped by Hamza, one of our Leicester registrars who I recently...

Demanding cases or nightmares in endourology? Nov/Dec 2017

Case 1 A 78-year-old male was transferred from a referring hospital. He had a cystectomy and ileal conduit performed 15 years previously and had recently been admitted with a clinical diagnosis of an infected obstructed kidney. The referring hospital had...

Demanding cases or nightmares in endourology? May/Jun 2016

In the third article in this series the authors describe their experience with the very rare indications for laparoscopic stone surgery. Case 1 A 44-year-old woman presented with several months of malaise and right flank pain. A CT scan demonstrated...

Infections and inflammation: Part 1

See also Part 2 and Part 3. Case 1 A 59-year-old man presented with right loin pain. His GP arranged for him to have an intravenous urogram (IVU) and subsequent CT urogram performed. What is the likely diagnosis? What are...

Benign upper tract abnormalities

Case 1 A 28-year-old lady has been referred to your clinic with right loin pain. She has no significant past medical history but mentions that she and her partner have been trying to get pregnant. She has an US renal...

Increasing patient hydration through technology

Achieving optimal hydration is crucial particularly for patients with nephrolithiasis. Research suggests that intake should approach 2.5–3.5 litres per day to allow for the daily excretion of 2–3 litres of dilute urine [1]. Unfortunately, patient compliance is known to be...

Ejaculatory dysfunction: a review of current practice and guidelines

Introduction The ejaculatory process is paramount to procreation in nature. It is a complex orchestration of physiology that results in emission of the ejaculate into the posterior urethra followed by ejection of those fluids from the urethra and orgasm. The...

UROsource

The European Association of Urology (EAU) has a new educational platform called UROsource, the learning library for urologists. The EAU library contains a searchable index of EAU conference proceedings, European Urology (EU) journals and EAU Guidelines. The searchable index is...

Ureterocystostomy – novel surgery for the paediatric obstructed megaureter

Megaureter is a relatively common congenital urinary tract anomaly; obstructed non-refluxing megaureter is one variant. Initial management is conservative, with operative intervention reserved for symptomatic cases (recurrent pyelonephritis, pain, increasing dilatation or worsening renal function). Surgical options include cutaneous ureterostomy,...

Abiraterone plus prednisone in metastatic, castration-sensitive prostate cancer

Abiraterone acetate, the prodrug of abiraterone, blocks endogenous androgen synthesis by inhibiting cytochrome p-450c17, a critical enzyme in androgen biosynthesis. Its active D4A metabolite also has anti-tumour effects through possibly multiple mechanisms. 3-5% of men diagnosed with prostate cancer in...