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The EP2 receptor – a novel target for prostate cancer?

1 July 2014 | | URO - Basic Science Research, URO - Urologic Oncology
This basic science paper sets out to evaluate the effects that celecoxib, a selective cyclo-oxygenase-2 (COX-2) inhibitor, have on prostate cancer cell lines and evaluated the mechanisms behind these effects. COX-2 induces the production of prostaglandins, which promote cell proliferation...

Managing sustainability

2 April 2024 |
Planetary health needs to be addressed at a societal level for any meaningful impact to occur. As the global director of sustainability for a law firm, Marion Palmer provides an overview of the responsibilities of corporate organisations for both a...

New drug hope for prostate cancer patients

16 January 2025
• Hormone therapy is used to slow the progression of advanced prostate cancer, but cancers often develop resistance and continue to grow.• Research reveals that patients with higher levels of heat shock proteins have worse outcomes.• Targeting these proteins with...

Artificial intelligence in bladder cancer diagnostics

2 May 2025 | | URO - Urologic Oncology
Bladder cancer (BCa), ranking as the 10th most common cancer worldwide, poses a significant health burden with high morbidity and mortality [1]. Timely tumour detection and accurate evaluation are crucial for effective management, as the prognosis is dependent on the...

Can we make LATE-presenting posterior urethral valves an EARLIER-treated condition?

3 September 2024 | | URO - Paediatric Urology
What are posterior urethral valves? Posterior urethral valve (PUV) is the most common cause of congenital bladder outlet obstruction (BOO) and renal failure in male children. They were first described by the Italian anatomist Giovanni Battista Morgagni back in the...

Congenital buried penis – an extremely rare entity

21 August 2024 | | URO - Paediatric Urology, URO - Functional / Reconstructive Urology, URO - Trauma & Emergency
Congenital non-visualisation of penis is a rare form of buried penis. It affects the functional and psychological behaviour of the affected child. Most of the cases in literature are secondary in nature like post circumcision, post trauma and due to...

Of gods and men

7 July 2020 | | URO - Technology
In this series of articles I am going to show you some of the exhibits contained in the Museum of Urology, hosted on the BAUS website (www.baus.org.uk). One of the most fascinating aspects of early Ancient Greek culture is the...

‘The Rise of a Specialty’ – Exhibition at the Royal Society of Medicine

4 May 2020 | | URO - Technology
The founding of the Royal Society of Medicine’s (RSM) Urology Section 100 years ago this year was crucial to the establishment of urology as a specialty in Great Britain in its own right. To mark this anniversary, earlier this year...

Renal masses

2 March 2022 | | URO - Urologic Oncology
Case 1 A 70-year-old female presented under the medical team with malaise, weight loss, and deranged liver function tests (LFTs) and calcium (ALP 350, GGT 650, Serum bilirubin 29, normal aminotransferases, Ca 3.3). An abdominal ultrasound scan (USS) was performed...

Infections and inflammation: Part 3

1 May 2019 | URO - Functional / Reconstructive Urology, URO - Infection, URO - Andrology, URO - Trauma & Emergency
See also Part 1 and Part 2 Case 1 You review a man in the Emergency Department with scrotal pain and sepsis. His clinical examination findings are shown. What does this image show? Who was this condition named after? What...

A sigma six approach to improving nephrostomy and antegrade stent services at a district general hospital – an audit project

12 September 2023 | | URO - Trauma & Emergency
As hospitals merge into larger trusts there becomes a centralisation of some services. Interventional radiology (IR) has been one of those services. Our district general hospital runs bi-weekly lR lists following service centralisation. Urology and IR most commonly liaise on...

Establishing a new TPPBx service during the COVID-19 pandemic

6 November 2020 | | URO - Urologic Oncology, URO - Technology
COVID-19 had a major impact on our hospital services from early in the pandemic, with almost three times as many patients being ventilated compared to the normal ITU capacity at the beginning of April. During the build-up to this point,...