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MRI screening for prostate cancer: a step towards a ‘prostagram’

7 January 2020 | | URO - Urologic Oncology, URO - Technology
The UK National Screening Committee has been calling for further research into alternative screening tests for prostate cancer. The committee decided against prostate cancer screening using prostate specific antigen (PSA) testing on the basis that “PSA is still a poor...

Medical statistics for urologists: part 2 – probability and hypothesis testing

2 March 2022 |
Following on from Part 1 of this series (Part 3 available here), this article aims to build on other analytical techniques commonly used within medical research, focusing on simple examples. Probability and testing Before exploring hypothesis testing, it is vital...

MOWOOT II Intestinal Transit Management System

1 November 2020 | Research & Development
MOWOOT II is an intermittent colonic exo-peristaltic therapy system for intestinal transit disorders, such as slow transit constipation. MOWOOT II utilises advanced pneumatic technology to treat and prevent chronic constipation without laxatives, enemas...

Improving on the Rotterdam Prostate Cancer Risk Calculator

1 January 2019 | | URO - Technology
Following the PROMIS trial [1], many cancer centres in the UK are now offering pre-biopsy multiparametric MRI (mpMRI) for men suitable for radical treatment. The European Association of Urology for Prostate Cancer (PCa) guidelines recommend individual risk stratification before the...

Diving into unfamiliar water – volunteering in critical care

28 January 2021 | | URO - Core Urology, URO - Trauma & Emergency
On the 14th and 15th floor of The Royal London Hospital lay rows of patients infected with COVID-19 battling for their lives at The Queen Elizabeth unit. In response to the pandemic, the hospital rapidly expanded their critical care facility...

Pushing the boundaries of urological research with trainee-led collaboration in the BURST Research Collaborative

1 March 2016 | | URO - Core Urology
Background: the concept of trainee-led research Over the past five years a novel and exciting collaborative approach to delivering research has been developed in the UK. Trainee-led regional and national research networks have been introduced, with the greatest success seen...

Priapism in sickle cell disease

2 March 2022 | | URO - Andrology
What is sickle cell disease? Sickle cell disease (SCD) is one of the most common single-gene disorders in the UK affecting approximately one in every 2000 live births. Approximately 20-25 million people worldwide have SCD. It predominately affects those of...

Focal therapy for prostate cancer – ready for prime time?

1 November 2016 | | URO - Basic Science Research, URO - Urologic Oncology
The current therapeutic ratio for radical therapy in many men with localised prostate cancer is not ideal. For a significant side-effect profile, there seems to be a small survival benefit over a 10-15 year period. A strategy that might balance...

The role of transperineal template biopsies in the diagnosis of prostate cancer

1 March 2014 | | URO - Urologic Oncology
The case In 2002, Mr A, a 64-year-old software engineer, was referred by his GP for further investigation of a raised prostate specific antigen (PSA) of 6.2. His prostate felt benign. He underwent transrectal ultrasound guided (TRUS) prostate biopsies. This...

Use of MRI in the evaluation of prostate cancer: part 2

1 March 2015 | | URO - Urologic Oncology, URO - Uroradiology
Diffusion weighted imaging and contrast enhanced imaging Introduction Magnetic resonance imaging (MRI) is widely used in localisation, staging and post-treatment follow-up of prostate cancer. In the previous issue, we discussed the usefulness of MRI in depicting prostate anatomy and pairing...

Demanding cases or nightmares in uro-oncology? Sep/Oct 2021

3 September 2021 | | URO - Urologic Oncology
Active surveillance for prostate cancer: missing the boat Case In 2005 a 43-year-old man of Afro-Caribbean ethnicity was referred to our centre for investigation of suspected prostate cancer. Digital rectal exam revealed a firm right lobe, PSA of 2.3ng/ml, prostate...

Focal therapies in prostate cancer

1 November 2018 | | URO - Urologic Oncology, URO - Technology
The standard of care in the management of prostate cancer has, to date, always been to treat the whole gland. This has ranged from surveillance, surgical excision / prostatectomy or external beam radiotherapy / whole gland brachytherapy. With the evolution...