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Tissue-based biomarkers steering clinical decisions in patients with urothelial cancer
Biomarkers play an essential role in the diagnosis and treatment of urothelial cancer (UC), with PD-L1, FGFR, and MMR proteins being the most clinically established. These biomarkers, derived from histological specimens, guide therapeutic decisions for bladder cancer (BCa) and upper...Bladder cancer: where are we with intravesical therapies?
In the United Kingdom, almost 10,500 new cases of bladder cancer were identified in 2013, with over 5000 deaths in 2012 [1]. Seventy percent of new cases will be non-muscle invasive bladder cancer (NMIBC) at diagnosis and therefore will be...SIU (Société Internationale d'Urologie) 2025 Trainee Scholarship: An essential part of the SIU mission
SIU Congresses are the perfect opportunity to expand your knowledge and learn from world-renowned experts. To facilitate the education and training of urologists, SIU offers a merit-based scholarship for select residents / fellows from countries the World Bank classifies as...Rishi Sunak joins Prostate Cancer Research as an ambassador
Rishi Sunak with three prostate cancer patients at the Oxford BioDynamics labs. (From left to right: Dafydd Charles, Briane Milne, Rishi Sunak, Alfred Samuels). Former UK Prime Minister Rishi Sunak has joined Prostate Cancer Research as an ambassador, to champion...Urology National Selection: tips and tricks for a successful interview process
We invited Dominic Brown, the top-ranking candidate from the Urology National Training Selection Interview 2023, to share his wisdom on the interview process. Dominic is currently an ST3 working in North West London. Kelly Ong, Urology News Trainees Sub-Editor. 1....
Outcomes of preserving the foreskin during distal hypospadias
Hypospadias surgery continues to tax the minds of paediatric urologists. Increasingly distal hypospadias surgery is becoming more and more conservative (in some cases, carrying out only foreskin reconstruction and leaving a mild hypospadias) and the role of foreskin reconstruction as...Suprapubic catheterisation – a core surgical trainee’s perspective
Suprapubic catheters (SPCs) are in widespread usage in medical practice and this review will focus on the pre-assessment, indications, methods and complications that are associated with the insertion of an SPC. Although suprapubic catheter insertions may be done electively or...
The potential of statin use in castrate resistant prostate cancer treatment
One of the mechanisms by which prostate cancer achieves castrate resistance is through de novo intratumoral production of androgens. Reactivation of androgen receptors results in promotion of cell survival and proliferation pathways despite castrate serum testosterone levels. As androgen synthesis...
Prenatal spina bifida repair – does it have urological benefits in the longer term?
At present, I have one patient under my care who underwent prenatal closure of his spina bifida defect. Only with time, will we be able to determine whether this intervention has been of benefit for him from a urological standpoint....
Robotic Urology
This represents a well written and comprehensive tome covering virtually all aspects of kidney, bladder and prostate surgery. The opening chapters deal well with aspects relating to robotic anaesthesia, training and education which I suspect even the most experienced of...The effect of COVID-19 on urology training
COVID-19 has affected all aspects of medicine. Urologists have been called upon to work in vastly different working environments including acute pan-surgical teams, intensive care and medical wards. The strategies put in place by hospital management teams vary significantly across...
