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A phase II dose-ranging study of mirabegron in patients with OAB

1 March 2014 | | URO - Functional / Reconstructive Urology
This was a multinational, multicentre, randomised, double–blind, double-dummy, parallel group placebo- and active- controlled phase II study. The study enrolled 1108 men and women aged 18 and over. The criteria were: patients must have had overactive blader (OAB) symptoms for...
The Journal of Urology cover image with Online Exclusive stamp

Trade-offs between risks and benefits of localised prostate cancer treatments – the COMPARE study

4 September 2020 | | URO - Urologic Oncology
We know little about the trade-offs men make when considering the oncological and functional outcomes of individual treatment options for localised prostate cancer, and decisions are often influenced by physician opinion. The likely compromised functional results are viewed as a...

iMEDicare – Pelvic Health Naturally are on a mission

12 June 2025
Since 2022, the team at iMEDicare has been scaling the highest peaks of various European nations to raise funds for a selection of their favourite charities. Their mountain adventures have so far taken them to the top of Scotland, Wales,...

Convatec Healthcare is changing

11 May 2023
Forever Caring At Convatec, ‘forever caring’ is our promise to give patients and healthcare providers the support they need as we bring to life our vision of pioneering trusted medical solutions to improve the lives we touch. Existing complications of...

Children’s bowel and bladder health takes centre stage in World Continence Week

26 June 2025
World Continence Week (16–22 June in 2025) is an annual global awareness campaign that shines a spotlight on bowel and bladder issues. This year, the focus was on children, as ERIC, The Children’s Bowel and Bladder Charity brought the issue...

What is new in lasers for endourology: looking into the future

7 January 2021 | | URO - Endourology & Stones, URO - Technology
From the first cystoscopic argon and neodymium-YAG (yttrium-aluminium-garnet) laser used for bladder tumours in 1976 by Staehler et al. [1], lasers have proven to be a versatile and an evolving tool in the therapeutic management of a variety of urological...

Intravesical GAG replacement therapies for bladder pain syndrome / interstitial cystitis – an update

4 May 2020 | | URO - Functional / Reconstructive Urology, URO - Infection, URO - Basic Science Research
The barrier function of the glycosaminoglycan (GAG) layer of the urothelium was identified by Parsons in 1975, and intravesical therapies to treat chronic inflammatory conditions of the bladder were developed soon after. However, the active role of the urothelium in...

Developing a core outcome set for male fertility trials

4 September 2025 | | URO - Basic Science Research, URO - Andrology
Advances in fertility treatment since in vitro fertilisation was pioneered by Edwards and Steptoe, cumulating in the birth of Louise Brown in 1978, have been nothing short of remarkable [1]. Since then, a myriad of treatments has been developed for...

The burning issue of urinary tract infections

1 September 2018 | | URO - Infection, URO - Functional / Reconstructive Urology
Urinary tract infections (UTIs) occur when bacteria colonise and proliferate in the urinary tract. These are characterised by specific clinical symptoms (dysuria, suprapubic tenderness, urgency and urinary frequency) which commonly occur alongside the finding of bacteriuria. UTIs are common –...

New techniques in UTI diagnosis

12 September 2023 | | URO - Functional / Reconstructive Urology, URO - Infection
Urinary tract infection (UTI) is a common reason for seeking medical care in both primary and secondary settings. Half of women will have at least one episode of cystitis in their lifetime, and a third of them will have experienced...

Current developments and innovations of the WASHOUT study: A large-scale observational study of inpatient haematuria

8 January 2025 | | URO - Trauma & Emergency, URO - Functional / Reconstructive Urology, URO - Infection
Unscheduled haematuria admissions ranks among the most common urological emergencies, yet its investigation and management still lack standardisation. The readmission rate for haematuria is substantial, with reports as high as 8%, and the median hospital stay for such cases in...

Should it be a mandatory requirement for medical students to receive the COVID-19 vaccine to attend clinical attachments?

11 August 2021 | | URO - Core Urology
The vast majority of medical students have positive attitudes towards the COVID-19 vaccine for themselves and patients, however, what about the small inevitable minority who resist it? Should they be prevented from attending clinical attachments in the NHS? It is...