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Adrenal incidentalomas: what next?

8 January 2024 | | URO - Urologic Oncology, URO - Functional / Reconstructive Urology
An incidentaloma refers to an adrenal lesion >1cm discovered incidentally during radiologic examination. Identifying a malignant and / or functioning lesion is critical for management. However, as the majority of lesions are benign, the challenge is the identification of malignant...

Clear cell urothelial carcinoma: a highly aggressive morphological variant in the bladder and upper urinary tract

2 November 2023 | | URO - Urologic Oncology
Clear cell urothelial carcinoma (CCUC) is a rare morphological variant of transitional cell carcinoma (TCC). It can occur anywhere along the urothelial tract and is characterised histologically by high grade carcinoma with an abundance of clear, glycogen-rich cytoplasm [1]. Alternative...

Onco-fertility: a review

7 January 2020 | | URO - Andrology, URO - Urologic Oncology
Subfertility or infertility is a major problem affecting men diagnosed with testicular cancer (TC) either due to the disease itself [1], or as a result of management [2]. TC is the most prevalent cancer affecting men of reproductive age [3]....

The PROMIS trial – time for multi-parametric MRI before a first prostate biopsy

1 March 2017 | | URO - Uroradiology, URO - Urologic Oncology
Whilst the relatively random process of 12 core transrectal ultrasound guided (TRUS) prostate biopsy remains by far the most widely employed approach to prostate cancer diagnosis in the UK, its flaws as a standalone diagnostic strategy are increasingly apparent. TRUS-biopsy...

Bladder cancer: where are we with intravesical therapies?

1 July 2016 | | URO - Urologic Oncology
In the United Kingdom, almost 10,500 new cases of bladder cancer were identified in 2013, with over 5000 deaths in 2012 [1]. Seventy percent of new cases will be non-muscle invasive bladder cancer (NMIBC) at diagnosis and therefore will be...

Renal calculi composition – Hounsfield units or dual energy CT?

1 July 2014 | | URO - Endourology & Stones, URO - Uroradiology
In this, the inaugural uro-radiology article, Jane Belfield (Section Editor) considers the significance of Hounsfield units in defining stone composition. Despite its widespread adoption and referencing in stone MDTs, there are some very clear limitations. Jane explores the potential role...

Using change theories can help nurses implement better care in prostate cancer

6 November 2024 | | URO - Urologic Oncology
Nurses can help support change in prostate cancer care by understanding change management and models and provide leadership in improving prostate cancer care. An important part of being able to lead change is to understand change theories such as the...

Sarcomatoid renal cell carcinoma

1 September 2017 | | URO - Urologic Oncology
Renal cell carcinoma (RCC) represents 2-3% of all cancers [1]. It is an adenocarcinoma making up 85% of all renal malignancies. Sarcomatoid transformation is a microscopically identified feature of RCC accounting for 5% of all RCCs [2]. Known as sarcomatoid...

Trials offering cytoreductive surgery for men with de novo synchronous metastatic prostate cancer

8 November 2021 | | URO - Basic Science Research, URO - Urologic Oncology
Life expectancy in men diagnosed with de novo synchronous metastatic hormone-sensitive prostate cancer (mHSPC) has risen to a median of 4.8 years with upfront systemic agents (such as docetaxel) in addition to standard androgen deprivation therapy (ADT) [1-3]. Within this...

Complications of CISC

1 July 2014 | | URO - Infection, URO - Functional / Reconstructive Urology, URO - Neurourology
Introduction Clean intermittent self catheterisation (CISC) was first introduced and popularised by Lapides in 1972. Since then its utilisation has become widespread and it is now commonly used throughout the world as the preferred means of facilitating complete and effective...