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Increasing PSA after negative prostate biopsy - solving the clinical puzzle

1 November 2014 | | URO - Urologic Oncology
There are standard guidelines for first transrectal ultrasonography (TRUS) guided biopsy in a patient presenting with elevated prostate-specific antigen (PSA) or suspicious digital rectal examination (DRE) findings. Patients are generally warned before a TRUS biopsy in respect of a false...

New CPD Course Advances LATP Biopsy Skills for Clinicians

9 May 2025 | Company Profiles, Research & Development
Mermaid Medical, in collaboration with Fujifilm, recently delivered the first session of a new CPD-accredited training course focused on Local Anaesthetic Transperineal Prostate (LATP) biopsy procedures. Hosted at the advanced Fujifilm House in Bedford, the workshop welcomed healthcare professionals for...

The role of embolisation in urology

3 September 2024 | | URO - Functional / Reconstructive Urology, URO - Urologic Oncology
Case 1 An 86–year–old male presented with visible haematuria and suprapubic pain. He had a history of diabetes, heart failure, benign prostatic hypertrophy, aortic valve replacement, deep vein thrombosis (DVT) and atrial fibrillation (AF) and was anticoagulated on a non-VKA...

The PROMIS trial – time for multi-parametric MRI before a first prostate biopsy

1 March 2017 | | URO - Uroradiology, URO - Urologic Oncology
Whilst the relatively random process of 12 core transrectal ultrasound guided (TRUS) prostate biopsy remains by far the most widely employed approach to prostate cancer diagnosis in the UK, its flaws as a standalone diagnostic strategy are increasingly apparent. TRUS-biopsy...
European Urology journal front cover.

Multiparametric MRI with targeted-only biopsy – a new standard?

21 November 2025 | | URO - Urologic Oncology
In this issue of European Urology, Kasivisvanathan et al. present a meta-analysis of two randomised trials comparing prebiopsy MRI with targeted biopsy (TBx) alone versus standard transrectal ultrasound-guided biopsy (TRUS-Bx) in biopsy-naïve men at risk of prostate cancer. Their findings...

Cortical stimulation for voiding dysfunction in multiple sclerosis

12 October 2022 | | URO - Functional / Reconstructive Urology, URO - Neurourology
Voiding dysfunction (VD) increases morbidity in patients with multiple sclerosis (MS), and may be associated with urinary tract infections, stones and renal failure. Catheterisation is required when impaired hand function precludes self-catheterisation, which is associated with further morbidity. In this...

The assessment and medical treatment of LUTS secondary to BPH

1 November 2016 | URO - Functional / Reconstructive Urology
The term benign prostatic hyperplasia (BPH) describes prostate enlargement due to non-cancerous processes. Several aetiological mechanisms are involved, including hormonal and vascular alterations; abnormal regulation of apoptosis; and prostatic inflammation, which may stimulate cellular proliferation. With ageing, prostate enlargement can...

Recent developments in bladder cancer

1 September 2018 | | URO - Urologic Oncology
There have been some exciting developments in bladder cancer over the last few years. Immunotherapy has prolonged survival in a proportion of patients with metastatic disease, with sustained efficacy in some. Advances in genetic analysis and molecular subtyping make personalised...

Urinary biomarkers for surveillance of non-muscle invasive bladder cancer

1 May 2019 | | URO - Basic Science Research, URO - Urologic Oncology
Bladder cancer (BC) is the ninth most common cancer worldwide with a yearly incidence of approximately 430,000 cases. There is a male predominance and it is the seventh most common cancer in men worldwide [1]. Non-muscle invasive bladder cancer (NMIBC)...

Balanitis xerotica obliterans

1 September 2018 | | URO - Andrology, URO - Urologic Oncology
Balanitis xerotica obliterans (BXO) / lichen sclerosus of the male genitalia is a common cause of acquired phimosis, and was first described by Stuhmer in 1928 [1]. It is described in medical literature as a chronic inflammatory condition of unknown...

Urethral diverticulum: a review of the literature and local experience

1 May 2016 | | URO - Uroradiology, URO - Functional / Reconstructive Urology
Urethral diverticula are an uncommon finding on imaging. They are focal outpouchings of the urethra into the periurethral / urethrovaginal space, occurring more frequently in females (up to 6% of women) [1]. These diverticula are becoming more prevalent in clinical...

What’s new in post prostatectomy incontinence?

1 January 2017 | | URO - Functional / Reconstructive Urology
With an ageing population, the number of men being diagnosed with prostate cancer each year is steadily rising. With more specific investigations, such as multiparametric magnetic resonance imaging (MpMRI) and transperineal biopsies, the number of cases diagnosed at an earlier...