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HIV-related stone disease – a potential new paradigm?

This paper discusses the management of patients with stone disease and HIV. The chronic nature of HIV infection is due in large part to the effectiveness of anti-retroviral therapies (ART). However, the role of protease inhibitors has been widely discussed...

Thiazide diuretic prophylaxis for kidney stones and the risk of diabetes mellitus

Thiazide diuretics have been used to reduce calcium nephrolithiasis recurrence as it is tolerated well, inexpensive and reduces calcium excretion in urine. It has been linked with increased risk of diabetes mellitus (DM) in the presence of hypertension (ALLHAT study),...

Increasing PSA after negative prostate biopsy - solving the clinical puzzle

There are standard guidelines for first transrectal ultrasonography (TRUS) guided biopsy in a patient presenting with elevated prostate-specific antigen (PSA) or suspicious digital rectal examination (DRE) findings. Patients are generally warned before a TRUS biopsy in respect of a false...

PDE5I in LUTS – how do they work – no proof yet

Phosphodiesterase type 5 (PDE5) inhibitors used in erectile dysfunction (ED) have been shown to improve lower urinary tract symptoms (LUTS) as well. The mechanism is not well understood. One of the hypotheses for benign prostatic hyperplasia (BPH) – LUTS is...

Intravesical cytosine arabinoside + Mitomycin C for bladder cancer – is it beneficial?

Mitomycin C (MMC) is often used as an intravesical therapy for low / intermediate risk non-muscle invasive bladder cancer. This randomised controlled trial (RCT) was designed to assess the safety and efficacy of MMC + cytosine arabinoside (Ara-C). Ara-C was...

Hypospadias – how long should follow-up be?

The optimal duration of follow-up following childhood hypospadias repair (to detect complications) is ill-defined. Several surgeons recommend it to include assessment during puberty. Some may worry that ‘rapid penile growth’, ‘erectile forces’ and ‘sexual activity’ could potentially stress previously successful...

Effect of DUA on surgical outcomes of HoLEP

Lower urinary tract symptoms (LUTS) become increasingly common in men as they age, with over 70–90% of men aged over 80 experiencing these issues. Detrusor underactivity (DUA) is characterised by a weakened bladder contraction, leading to prolonged or incomplete bladder...

Effercitrate Tablets available to prescribe on FP10 from Cambridge Healthcare Supplies

Indicated for the relief of symptoms of cystitis in Adults & Children over 6years. Effercitrate Tablets, when dissolved in water, produce potassium citrate which provides effective alkalisation of urine, with a pleasant lemon and lime flavour.¹ Each tablet contains²: 1.5g...

Management dilemma for very high-risk non–muscle-invasive bladder cancer

The European Association of Urology (EAU) guidelines recommend upfront radical cystectomy (RC) for very high-risk (VHR) non-muscle-invasive bladder cancer (NMIBC). However, real-world adoption is limited, as most patients are reluctant to undergo immediate bladder removal. The EAU 2021 risk model...

New App supports home monitoring of urology conditions

Azur Innovation recently launched PQtap, a mobile application designed to support the home monitoring of a range of urology conditions. The app is available on Apple’s App Store and Google Play and may be recommended by healthcare professionals to patients...

NHS hospitals adopt GALEAS Bladder: a faster, more accurate at-home bladder cancer test

NHS hospitals are using a new way of testing for bladder cancer that is fast, accurate and convenient for patients, as profiled in The Guardian on 8 June 2026. GALEAS Bladder is enabling NHS hospitals to reduce procedures so cystoscopy...

Mo Belal: a journey of perseverance, resilience and representation

In this interview, we have the privilege of speaking with Mr Mo Belal, a leading consultant urologist whose career and life took an extraordinary turn following a spinal injury. Renowned for his expertise and dedication to patient care, Mr Belal...