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Intravesical GAG replacement therapies for bladder pain syndrome / interstitial cystitis – an update
The barrier function of the glycosaminoglycan (GAG) layer of the urothelium was identified by Parsons in 1975, and intravesical therapies to treat chronic inflammatory conditions of the bladder were developed soon after. However, the active role of the urothelium in...ICS updates in continence care: a personal perspective on the role of basic science in urology
At a urology research meeting in Sheffield a few years ago, a former post doctorate researcher in urology, Mathieu Boudes, said: “Stop calling it basic research, there is nothing basic about it. It is fundamental research to everything urologists do.”...
Adjustable Transobturator Male System® as a novel treatment for men with stress urinary incontinence
Stress urinary incontinence (SUI) in men is a debilitating condition, often occurring after prostate cancer surgery, with an incidence ranging from 4% to 40%. Key predictors of SUI post-prostatectomy include age, body mass index (BMI), comorbidity index, lower urinary tract...Prostate Cancer Vaccine Research Launched in Surrey
In September 2025, The Prostate Project, a Guildford-based volunteer-led charity, will launch a £250,000 campaign to raise funds for a prostate cancer research project widely anticipated to be ‘game-changing’. Work has begun to develop a vaccine to prevent the return...Prostate Scotland statement on National Screening Committee recommendation
Prostate Scotland notes the recommendation from the UK National Screening Committee (NSC) on Friday 28 November 2025 to introduce targeted prostate cancer screening only for men with confirmed BRCA1 or BRCA2 gene variants. While this represents an important first step...
A new haemostatic agent in tubeless PCNL
Tubeless percutaneous nephrolithotomy (PCNL) is increasingly being used in carefully selected patients to reduce hospital stay and analgesia requirements, especially in those with little bleeding who become stone free or have insignificant residual fragments (usually <4mm). Various agents have been...
Hypospadias – can urologists achieve the unachievable?
US News & World Report (USNWR) provide rankings on a wide range of topics (education, health, money, travel, cars and law firms). In terms of healthcare, they suggest that their rankings (based on metrics) are a tool that can help...
How can we reduce morbidity after RARC with intracorporeal neobladder?
Robot-assisted radical cystectomy (RARC) is a complex procedure with high postoperative morbidity, especially when combined with neobladder reconstruction, which has a higher complication rate compared to other urinary diversions. To minimise these complications, it is crucial to understand their nature...The microbial syndicate: dysbiosis and origins of recurrent UTIs
Traditional dogma held that urine was sterile. However, recent molecular studies have revealed an underground microbial community, known as the urinary microbiome or ‘urobiome’ [1]. Far from being harmful, this community of microorganisms helps modulate immune responses, regulate inflammation, and...Stereotactic body radiotherapy for oligometastatic disease secondary to urological cancer
The concept of oligometastatic disease is controversial. The traditional model of cancer, which most of us learnt at medical school, is of a disease which starts confined to an organ, for example the prostate, where it can be cured with...
Urology MDTs: what members think
This study aimed to examine the functionality of urology cancer multidisciplinary team meetings (MDTs). Evidence has suggested that urology MDTs are not as well structured as other surgical disciplines. MDT members were asked their views on if there were any...
