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Intermittent vs. continuous hormonal therapy for metastatic prostate cancer
Continuous androgen deprivation therapy (cADT) is the standard management for metastatic prostate cancer (mPCa). Intermittent androgen deprivation therapy (iADT) is sought to have better quality of life (QoL) and adverse events profile during off-treatment period. This multicentre European randomised study...
Prostate Cancer Diagnosis – PSA, Biopsy and Beyond
The danger of many of the texts which deal with this rapidly changing field is that by the time the texts are published they are out of date. This book however remains fresh, in part because it acknowledges that there...
Prostatic urethral lift for obstructive median lobes: 12-month results of the MedLift study
As the various new BPH therapies try and mark out their role in the management of the condition, this is an interesting and useful addition to the literature. Patients were clinically screened for an obstructive median lobe on cystoscopy, which...
Smoking and urological health
European Urology Focus is a new sister journal to European Urology. It is peer-reviewed and will be published six times per year in electronic format. The first issue deals with smoking and urological diseases. It makes for very interesting reading...Female and functional
Case 1 A 65-year-old woman presents with an 18-month history of “recurrent urinary tract infections” (rUTI). She is otherwise fit and well with no underlying medical problems and no lower urinary tract symptoms. What is the definition of a UTI...Viveca Biomed acquires Contrelle Activgard – European market launch imminent!
Viveca Biomed is pleased to announce the imminent relaunch of Contrelle Activgard across Europe, starting with the UK market.
Urinary diversion and infections
This article will be of interest to colleagues undertaking reconstructive surgery. Urinary diversions have been performed for decades. Common indications are muscle-invasive bladder cancer, neurological disorders, inflammatory conditions and congenital malformation. The diversions could be continent or non-continent. Complications due...
The EP2 receptor – a novel target for prostate cancer?
This basic science paper sets out to evaluate the effects that celecoxib, a selective cyclo-oxygenase-2 (COX-2) inhibitor, have on prostate cancer cell lines and evaluated the mechanisms behind these effects. COX-2 induces the production of prostaglandins, which promote cell proliferation...
Bladder urothelial neoplasms in children
Urothelial bladder neoplasms are rare in children, occurring in 0.1-0.4% of the population before the age of 20. There are no current paediatric guidelines to their management. This study retrospectively reviews the files of patients from three tertiary centres between...
Adolescents and adults in paediatric urology clinics
This elegant descriptive paper retrospectively reviewed cases seen in a paediatric urology clinic with respect to age, diagnosis and presentations in a major Brazilian city. Of 521 patients, 404 were <12 years old, 103 were between 12-18 and 14 were...Sexually transmitted infections
Case 1 A 27-year-old man presents to the clinic with multiple asymptomatic penile lesions. 1. What is the diagnosis? 2. What are the likely pathogens which cause these lesions? 3. What treatment options are available to treat these lesions? 4....
