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Dogs and humans share a bladder cancer biomarker: a new discovery that opens doors for early detection and treatment

9 September 2025
A new scientific study has identified a new molecular biomarker that could help doctors detect aggressive early-stage bladder cancer, such as high-grade non-muscle invasive bladder cancer (NMIBC), in both dogs and humans. This discovery advances our knowledge of how aggressive...

Clinical Trials 2 – key papers

1 March 2017 | URO - Basic Science Research
Clinical Trials 1 is available here. Case 1 This British study on haematuria clinic diagnostic yield was published in the British Journal of Urology International in 2006. The results are often asked in examinations! Edwards TJ, et al. A prospective...

New study shows UK may finally be ready for prostate cancer screening

27 February 2023 | URO - Urologic Oncology
Prostate Cancer UK study shows tens of thousands fewer men each year face unnecessary harm thanks to new screening techniques. New research by Prostate Cancer UK shows that the UK may finally be in a position to roll out a...

Ambulatory local anaesthetic implantation of percutaneous sacral nerve stimulators

11 July 2023 | | URO - Functional / Reconstructive Urology
Background The current treatment paradigm for detrusor overactivity (DO) and dysfunctional voiding (DV) includes conservative measures, pharmacotherapy, intravesical onabotulinum toxin A (Botox®), sacral nerve modulation (SNM / SNS) and urinary diversion as a last resort [1]. Incidence of DO is...

Advanced renal tumours

4 November 2025 | | URO - Urologic Oncology
Case 1 A 67-year-old gentleman underwent a CT scan after presenting with visible haematuria and weight loss. His comorbidities include hypertension, type II diabetes mellitis and hypercholesterolaemia. He is a smoker. Figure 1. Figure 2. What do Figures 1 and...

Immunotherapy in renal cancer

1 May 2019 | | URO - Basic Science Research, URO - Urologic Oncology
Renal cell carcinoma (RCC) is the sixth most common solid organ cancer in the UK. In 2018, there were 403,262 people diagnosed worldwide with the disease (2.2% of all cancer cases), and it accounted for 175,098 deaths in total (1.8%...

Sexual dysfunction following prostate cancer treatment

4 March 2024 | | URO - Andrology, URO - Urologic Oncology
Prostate cancer is common with over 52,300 new cases diagnosed annually in the UK; this is expected to rise by 15% between 2023-2025 and 2038-2040 [1]. Radical prostatectomy continues to be the most common form of radical treatment for men...

Trials offering cytoreductive surgery for men with de novo synchronous metastatic prostate cancer

8 November 2021 | | URO - Basic Science Research, URO - Urologic Oncology
Life expectancy in men diagnosed with de novo synchronous metastatic hormone-sensitive prostate cancer (mHSPC) has risen to a median of 4.8 years with upfront systemic agents (such as docetaxel) in addition to standard androgen deprivation therapy (ADT) [1-3]. Within this...

Thermal ablative techniques for small renal masses

1 July 2017 | | URO - Urologic Oncology, URO - Technology
The incidence of renal cell carcinoma has increased over the past decade which can be partly attributed to the increased use of imaging modalities [1,2]. Nephron sparing procedures for the management of small renal tumours have gained popularity which include...

Indeterminate renal lesions – a pragmatic imaging approach

1 November 2016 | | URO - Uroradiology
The incidence of renal cell carcinoma (RCC) in the UK has increased steadily over the last two decades, largely driven by the increasing use of abdominal imaging and the incidental detection of small renal lesions [1]. The majority of incidental...

An overview of changes to urology training

1 January 2017 | | URO - Core Urology
Paediatric urology training A review of paediatric emergency services in the UK involving general surgery, urology and paediatric surgery was initiated due to the problems encountered by the lack of suitable experience outside large paediatric surgical units to deliver emergency...

In conversation with Ahmed Ali

12 May 2025 | URO - Core Urology
We were delighted to chat to Ahmed Ali about the journey to pursing a urological career in the UK and his decision to found the Arabic-British Urological Society. You grew up in Iraq and went to university in Baghdad; what...