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Sepsis and antibiotics: the debate goes on
Sepsis statistics are staggering around the world. The UK Sepsis Trust estimates that there are around 150,000 cases of sepsis in the UK every year and it kills 44,000 patients per year. There are many different definitions and criteria; in...
Cord compression in cancer
This article will be of great interest to uro-oncologists. Vertebral metastasis occurs in 3-5% of all cancers (most commonly in prostate, breast and lung cancer). It can cause pain, vertebral collapse and cord compression. Data from the National Institute for...
Do adult men with untreated ventral penile curvature have adverse outcomes?
The history of ventral penile curvature if untreated in childhood is not known. The authors tried to assess this by performing an online survey of adults who had untreated ventral penile curvature using a Facebook advertised survey. Their outcome measures...
Research needs you
This was an eye-catching front cover headline for the BMJ. Is research as important as clinical duties? The answer has to be yes. Research takes place in every NHS hospital, albeit in a fragmented way. All of us have to...
Non-antibiotic options for recurrent UTI
Recurrent urinary tract infection (UTI) imposes a heavy burden on health services. By definition recurrent UTI is two infections in six months or three in one year. The annual incidence of single UTI is 30 per 1000 women. The Scottish...
Cumulative incidence of outcomes and urologic procedures after augmentation cystoplasty
The authors of this paper describe the cumulative incidence of outcomes and surgical procedures following paediatric augmentation cystoplasties in the USA. They included all children <18 years over an 11-year period in their study and used the Pediatric Health Information...
Urinary tract infections and antibiotics – the debate goes on
A large number of hospital patients and primary care patients suffer from recurrent urinary tract infection (UTI) and urosepsis. Some of these patients end up in intensive care units with multi-organ failure. New draft guidance from the National Institute for...
Psychosocial distress in parents of children with DSD
Disorders of sex development (DSD) are a rare set of medical conditions with prevalence rates ranging between 1:00 to 1:5000 births. Secondary atypical genitalia is seen in a subset. Psychosocial aspects have until recently been understudied. We know that some...
Advanced prostate cancer and chemotherapy
The treatment pathway for advanced prostate cancer is both puzzling and complex and varies from centre to centre in the UK. The National Prostate Cancer Audit Report 2019 for England and Wales shows that only a quarter of men with...
