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Keep an eye on Viagra™

Many of the side-effects and contra-indications of sildenafil and other phosphodiesterase 5 (PDE 5) inhibitors for erectile dysfunction have become well known to doctors and pharmacists over the years. This study from the United States collected case reports of adverse...

History of prostate biopsy – part 2

For Part 1 of this topic is available here. The major limitations of the transrectal ultrasound (TRUS) guided prostate biopsy (PBx) protocols are the risk of profound sepsis and the risk of persistently significant false negative rates, related to the...

Indeterminate renal lesions – a pragmatic imaging approach

The incidence of renal cell carcinoma (RCC) in the UK has increased steadily over the last two decades, largely driven by the increasing use of abdominal imaging and the incidental detection of small renal lesions [1]. The majority of incidental...

BAUP (British Association of Urological Pathologists) Macroscopy under the microscope

Macroscopy is a critical aspect of histopathology reporting that has generally received less attention than microscopy and is not uncommonly delegated to less experienced practitioners with limited guidance and supervision. A symposium discussing issues around macroscopic specimen examination was published in the March 2024 issue of the Journal of Clinical Pathology (2024;77:169-203). Based on this symposium, the British Association of Urological Pathologists (BAUP), the British Association of Gynaecological Pathologists (BAGP) and the Journal of Clinical Pathology are jointly organising a 2-day multi-speciality webinar.

Emphysematous pyelonephritis: a review

Introduction Emphysematous pyelonephritis (EPN) is an acute, severe, necrotising, bacterial infection of the renal parenchyma and surrounding tissues, with gas in the renal parenchyma, collecting system or perinephric tissue. Although it is rare, it is potentially life threatening and early...

Robotic Reconstructive Urology Clinical Observership at NYU Langone Health, New York: supported by The Urology Foundation Career Development Support Fund

Reconstructive urology is an important area of clinical need within our population. However, within the context of competing service priorities, it continues to face resource and training challenges. Across the UK, only a small number of centres currently offer a...

Priapism in children

I have to state a conflict of interest here for obvious reasons, being one of the authors. This paper reviews the English literature between 1980 and 2013 and summarises the clinical classification, aetiology, physiology and pathophysiology of paediatric priapism –...

Ketamine uropathy – an update

The first two case series that documented the association between urinary tract damage and recreational ketamine use were published 12 years ago [1,2]. Since then ketamine has maintained a controversial profile as an essential medication of expanding utility but with...

Prostate abscess

Prostate abscess (PA) is a relatively uncommon clinical condition which is often difficult to diagnose because clinical symptoms are non-specific. It may be associated with a significant fatality rate, estimated to be between 3% and 30%, which may reflect its...

Adrenal incidentalomas: what next?

An incidentaloma refers to an adrenal lesion >1cm discovered incidentally during radiologic examination. Identifying a malignant and / or functioning lesion is critical for management. However, as the majority of lesions are benign, the challenge is the identification of malignant...

Should expert genitourinary pathology review of orchiectomy specimens be mandatory?

This article contains recommendations from the European Association of Urology Guidelines Panel on Testicular Cancer and argues that centralised review of orchiectomy specimens by expert genitourinary pathologists would contribute to better patient management. Accurate pathological assessment is fundamental to the...

What is the significance of prostatic calcification?

This prospective study on men undergoing transrectal ultrasonography (TRUS) biopsies was performed to evaluate the prevalence and to classify prostatic calcification (PCalc) on TRUS and correlate the findings with histology. Images of the prostate were saved at three defined regions:...