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Bladder cancer outcomes in patients with spina bifida

1 May 2018 | | Paediatric Urology, Urologic Oncology | Bladder augmentation, Bladder cancer, Myelomeningocele, Spina bifida, Systematic review
These authors carried out a systematic review using PubMed and a number of terms to pick up studies with an underlying diagnosis of myelomeningocele and bladder cancer, with exclusions of cord injury, tuberculosis, schistosomiasis, or prior ureterosigmoidostomy. Their aim was...

Comparison of pathological stage in patients treated with and without neoadjuvant chemotherapy for high-risk UTUC

1 March 2019 | | Urologic Oncology | carcinoma, chemotherapy, kidney neoplasms, neoadjuvant therapy, transitional cell, ureteral neoplasms
High-risk upper tract urothelial carcinoma (UTUC) has been associated with poor survival outcomes. The authors evaluated the role of neoadjuvant chemotherapy in high-risk cases prior to radical nephroureterectomy (RNU) in terms of pathological stage of the final surgical specimen. A...

The adrenals

1 March 2018 | Andrology, Basic Science Research, Endourology and Stones, Functional Urology, Infection, Neurourology, Paediatric Urology, Reconstructive Urology, Technological Developments, Trauma and Emergency Urology, Urologic Oncology, Uroradiology
Case 1 A 45-year-old man undergoes a CT of his abdomen to stage a newly diagnosed bowel malignancy. What does the scan show? What findings on a CT scan suggest an adrenal lesion is benign? If the CT scan is...

Cryotherapy in prostate cancer

1 March 2015 | | Urologic Oncology | Cryotherapy, cryosurgery, cryoablation, subtotal cryotherapy, targeted focal therapy, prostate cancer, prostate
This review of the literature aims to summarise what is known in regards to outcomes in patients undergoing cryotherapy in a number of settings: whole gland, salvage and targeted focal therapy. It highlights that more prostate cancers are being diagnosed...

Outcomes of sarcomatoid differentiation in urothelial carcinoma

5 December 2022 | | Urologic Oncology | #BladderCancer, #scmsm, #uroonc, bladder cancer, neoadjuvant therapy, pathological outcomes, sarcomatoid differentiation, survival, urothelial carcinoma
Sarcomatoid differentiation is a rare variant of urothelial carcinoma (UC) seen in 0.6% of cases. Its response to neo-adjuvant chemotherapy (NAC) has not been well reported. The authors have done a retrospective analysis of patients undergoing cystectomy between 1995 and...

Comparative effectiveness of nephron sparing surgery vs ablation

1 May 2014 | | Urologic Oncology
Nephron sparing surgery (NSS) and minimally invasive modality of thermal ablation have attracted great attention as an alternative surgical treatment to radical nephrectomy (RN) for renal tumours <4cm. High quality evidence comparing disease specific survival (DSS) is lacking. This issue...

Use of Clavien-Dindo classification in urology part 1 – pelvic surgery

1 March 2016 | | Urologic Oncology
There is no widely accepted system to classify postoperative complications. It is necessary to compare the outcome and complications while validating a new surgical procedure or one of the surgical approaches of a particular condition. Several parameters have long been...

Is routine renal tumour biopsy associated with lower rates of benign histology following nephrectomy for small renal masses?

1 May 2019 | | Basic Science Research, Urologic Oncology | biopsy, carcinoma, kidney neoplasms, nephrectomy, pathology, renal cell, surgical
There has been a considerable increase in the detection of small renal masses (SRM). Approximately 20% of these turn out to be benign lesions on final histopathological analysis. Therefore upfront surgery can be overtreatment in such a group of patients....

Trials offering cytoreductive surgery for men with de novo synchronous metastatic prostate cancer

8 November 2021 | | Basic Science Research, Urologic Oncology
Life expectancy in men diagnosed with de novo synchronous metastatic hormone-sensitive prostate cancer (mHSPC) has risen to a median of 4.8 years with upfront systemic agents (such as docetaxel) in addition to standard androgen deprivation therapy (ADT) [1-3]. Within this...

Post radical nephrectomy presenting with skull metastasis

10 April 2024 | | Urologic Oncology
We present the case of an 83-year-old female who underwent right radical nephrectomy for renal cell carcinoma (RCC). Despite negative surgical margins, the patient presented with a skull metastasis six years post radical nephrectomy. This case highlights the importance of...

Sarcomatoid renal cell carcinoma

1 September 2017 | | Urologic Oncology
Renal cell carcinoma (RCC) represents 2-3% of all cancers [1]. It is an adenocarcinoma making up 85% of all renal malignancies. Sarcomatoid transformation is a microscopically identified feature of RCC accounting for 5% of all RCCs [2]. Known as sarcomatoid...

Robotic assisted retroperitoneal partial nephrectomy with intraoperative ultrasound & 3D vascular

14 January 2020
Course Director: Mr Faiz Mumtaz, Consultant Urologist. This unique one day training course combines live surgery robotic-assisted laparoscopic partial nephrectomy (RALPN) procedures with intraoperative ultrasound imaging. Aimed at Consultants wishing to develop their expertise and improve surgical outcomes in RALPN....