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Intravesical GAG replacement therapies for bladder pain syndrome / interstitial cystitis – an update

4 May 2020 | | URO - Functional / Reconstructive Urology, URO - Infection, URO - Basic Science Research
The barrier function of the glycosaminoglycan (GAG) layer of the urothelium was identified by Parsons in 1975, and intravesical therapies to treat chronic inflammatory conditions of the bladder were developed soon after. However, the active role of the urothelium in...

Early British pioneers of urological imaging

1 September 2019 | | URO - Uroradiology, URO - Technology
In this series of articles I am going to show you some of the exhibits contained in the Museum of Urology, hosted on the BAUS website (www.baus.org.uk). In this article I am joined by Gavin Gordon of Newcastle University whose...

Demanding cases or nightmares in endourology? May/Jun 2016

1 May 2016 | | URO - Endourology & Stones
In the third article in this series the authors describe their experience with the very rare indications for laparoscopic stone surgery. Case 1 A 44-year-old woman presented with several months of malaise and right flank pain. A CT scan demonstrated...

Demanding cases or nightmares in endourology? Sep/Oct 2015

1 September 2015 | | URO - Endourology & Stones
One of the most interesting aspects of attending international meetings is the rare but invaluable, honest presentation of complex cases. We aim to present the readers with some complex and challenging ongoing cases in endourology. Case 1 A general practitioner...

I wasn’t expecting that! A series of unexpected radiology findings

1 July 2017 | URO - Uroradiology
Case 1 A 76-year-old diabetic man with a long-term catheter presents to the Emergency Department with rigors and non-specific abdominal pain. He has an elevated white cell count (WCC) and C-reactive protein (CRP). An abdominal and pelvic CT scan was...

Prostate cancer

1 July 2015 | | URO - Urologic Oncology
Case 1 What is prostate specific antigen (PSA) and what is its function? According to the ERSPC Trial (at 13 years), what was the number needed to screen and diagnosed to prevent one prostate cancer death and what was the...

Ambulatory local anaesthetic implantation of percutaneous sacral nerve stimulators

11 July 2023 | | URO - Functional / Reconstructive Urology
Background The current treatment paradigm for detrusor overactivity (DO) and dysfunctional voiding (DV) includes conservative measures, pharmacotherapy, intravesical onabotulinum toxin A (Botox®), sacral nerve modulation (SNM / SNS) and urinary diversion as a last resort [1]. Incidence of DO is...

Intelligent triage: improving outpatient efficiency

13 March 2023 | | URO - Andrology, URO - Basic Science Research, URO - Endourology & Stones, URO - Infection, URO - Neurourology, URO - Paediatrics, URO - Core Urology, URO - Functional / Reconstructive Urology, URO - Technology, URO - Trauma & Emergency, URO - Urologic Oncology, URO - Uroradiology
Background Improving outpatient (OP) efficiency and service structure is of paramount importance as the NHS seeks to manage ever increasing demand in the wake of the COVID-19 pandemic. As we re-establish services and attempt to clear the backlog, new ways...

Intravesical glycosaminoglycan analogue instillations for recurrent cystitis

1 May 2017 | | URO - Infection, URO - Functional / Reconstructive Urology
Introduction The symptoms of recurrent cystitis can be triggered by inflammatory or infective causes. Bladder pain syndrome (BPS) and bacterial recurrent lower urinary tract infection can both present with symptoms of recurrent cystitis and cause significant morbidity in affected individuals....

Challenges of catheter associated urinary tract infection: is prevention better than cure?

1 November 2017 | | URO - Infection, URO - Functional / Reconstructive Urology
Catheterisation is a common medical procedure in which a catheter (a hollow flexible tube) is inserted into the bladder in order to facilitate the drainage of urine. Catheters are usually passed into the bladder via the urethra, either to be...

Trials offering cytoreductive surgery for men with de novo synchronous metastatic prostate cancer

8 November 2021 | | URO - Basic Science Research, URO - Urologic Oncology
Life expectancy in men diagnosed with de novo synchronous metastatic hormone-sensitive prostate cancer (mHSPC) has risen to a median of 4.8 years with upfront systemic agents (such as docetaxel) in addition to standard androgen deprivation therapy (ADT) [1-3]. Within this...

Priapism

7 January 2021 | | URO - Andrology
Priapism is defined as an abnormally persistent erection lasting greater than four hours, not associated with sexual desire [1]. Although relatively uncommon with an incidence of 1.5 per 100,000 [2], priapism has a risk of complications which can have a...