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The microbial syndicate: dysbiosis and origins of recurrent UTIs

2 July 2025 | | URO - Basic Science Research, URO - Infection
Traditional dogma held that urine was sterile. However, recent molecular studies have revealed an underground microbial community, known as the urinary microbiome or ‘urobiome’ [1]. Far from being harmful, this community of microorganisms helps modulate immune responses, regulate inflammation, and...

Patient decision aids in the management of stress urinary incontinence

9 March 2020 | | URO - Functional / Reconstructive Urology
Urinary incontinence is a common condition faced by up to 20-50% of women, which impairs quality of life and poses a significant socioeconomic burden to both the individual women involved and more widely to the NHS [1]. The overall cost...

In conversation with Carmel Ramage

26 November 2025 | URO - Core Urology
Carmel Ramage. Can you tell us a little bit about what first attracted you to medicine and then what led you to specialise in urogynaecology? To be honest, I’m not sure I ever really made a conscious decision about my...
The Lancet journal cover image.

SUSPEND suspended MET

1 July 2015 | | URO - Endourology & Stones
This review is on the recent groundbreaking evidence on medical expulsive therapy (MET). MET using alpha adrenergic blockers (like tamsulosin) are in regular clinical practice. Even though it is an off label prescription, it is well accepted and practised world...
European Urology journal front cover.

Anti-VEGF and PD-1 combinations in renal cell carcinoma

2 July 2025 | | URO - Urologic Oncology
Over the past decade, vascular endothelial growth factor (VEGF) tyrosine kinase inhibitors (TKIs) have been central to treating renal cell carcinoma (RCC), with oncologists refining dosing strategies to balance treatment efficacy with quality of life (QoL). Recently, the introduction of...

Innovative catheter receives “bacteria-phobic™” claim approval from notified body: positive evaluation affirms device resistance to bacterial colonisation

4 September 2019 | Research & Development
Camstent Ltd’s coated catheter, which has been developed to limit attachment of bacteria to its surfaces, a known source of Catheter Acquired Urinary Tract Infection (CAUTI), has been awarded approval...

Mitrofanoff Support – 2019 Report

11 December 2019
Mitrofanoff Support is a charity that serves 600 members from more than 20 countries, with more than 1,600 people on our closed Facebook group. As such, we can claim to be the largest support network of Mitrofanoffers in the world, and as awareness continues...

Mentorship and its role in surgical training

6 November 2020 | | URO - Core Urology
Is there a principle which could help address multiple challenges in surgical training? One which has potential to improve recruitment and retention of staff to our specialty, quality of patient care and surgeon morale? The author discusses the past present...

Prostate cancer

1 July 2015 | | URO - Urologic Oncology
Case 1 What is prostate specific antigen (PSA) and what is its function? According to the ERSPC Trial (at 13 years), what was the number needed to screen and diagnosed to prevent one prostate cancer death and what was the...

The expanding indications for ureteroscopy – ad maiora!

1 March 2019 | | URO - Endourology & Stones, URO - Paediatrics, URO - Technology
The management of urolithiasis is becoming a Herculean task for healthcare providers worldwide. The incidence of stone disease is rising, with predicted lifetime risk of 12% in males and 6% in females [1]. This rise relates to both improving imaging...

Demanding cases or nightmares in endourology? Nov/Dec 2017

1 November 2017 | | URO - Endourology & Stones
Case 1 A 78-year-old male was transferred from a referring hospital. He had a cystectomy and ileal conduit performed 15 years previously and had recently been admitted with a clinical diagnosis of an infected obstructed kidney. The referring hospital had...

Urological trauma – part 2

1 November 2015 | | URO - Trauma & Emergency
Part 1 of this topic is available here. Case 1 A 29-year-old male was attacked and kicked in his left flank. He presented to the emergency department with left flank pain and frank haematuria. He remained haemodynamically stable. 1. What...